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Recombinant Human IGFBP-3 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      P4128
    • Availability
      Product Discontinued

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Recombinant Human IGFBP-3 Protein Summary

Description
IGFBP-3 (Human) Recombinant Protein

Source: E. coli

Amino Acid Sequence:
Preparation
Method
Escherichia coli expression system
Details of Functionality
The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is < 0.2 mg/mL, in the presence of 15 ng/mL of human IGF-II.
Protein/Peptide Type
Recombinant Protein
Gene
IGFBP3

Applications/Dilutions

Dilutions
  • Functional
  • SDS-Page
Application Notes
This product is useful for and SDS-PAGE and Functional assays.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from 20 mM HCl
Preservative
No Preservative
Reconstitution Instructions
Reconstitute with deionized water to desired concentration.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human IGFBP-3 Protein

  • acid stable subunit of the 140 K IGF complex
  • binding protein 29
  • binding protein 53
  • growth hormone-dependent binding protein
  • IBP-3
  • IBP3BP-53
  • IGF-binding protein 3
  • IGFBP3
  • IGFBP-3
  • insulin-like growth factor binding protein 3
  • insulin-like growth factor-binding protein 3

Background

IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

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Recombinant Human
IGFBP-3 Protein
P4128
Recombinant Human IGFBP-3 Protein
Species: Hu
Applications: Func, PAGE

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Bioinformatics

Gene Symbol IGFBP3