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Recombinant Human IGFBP-1 Protein

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Product Details

Summary
Product Discontinued
View other related IGFBP-1 Peptides and Proteins

Order Details


    • Catalog Number
      P4127
    • Availability
      Product Discontinued

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Recombinant Human IGFBP-1 Protein Summary

Description
IGFBP-1 (Human) Recombinant Protein

Source: Mouse

Amino Acid Sequence:
Preparation
Method
Mammalian cell (NSO) expression system
Details of Functionality
The ED50 as determined by its ability to inhibit IGF-I induced proliferation of NUC-1 cells is ~100 ng/mL.
Protein/Peptide Type
Recombinant Protein
Gene
IGFBP1

Applications/Dilutions

Dilutions
  • Functional
  • SDS-Page
Application Notes
This product is useful for and SDS-PAGE and Functional assays.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from 10 mM HCl
Preservative
No Preservative
Reconstitution Instructions
Reconstitute with deionized water to desired concentration.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human IGFBP-1 Protein

  • alpha-pregnancy-associated endometrial globulin
  • amniotic fluid binding protein
  • binding protein-25
  • binding protein-26
  • binding protein-28
  • growth hormone independent-binding protein
  • hIGFBP-1
  • IBP1
  • IBP-1
  • IGF-binding protein 1
  • IGFBP1
  • IGFBP-1
  • IGF-BP25
  • insulin-like growth factor binding protein 1
  • insulin-like growth factor-binding protein 1
  • Placental protein 12
  • PP12AFBP

Background

IGFBP1 is a gene that codes for an IGF-binding protein that circulates in the plasma and prolongs the half-life of IGFs and works to either inhibit of stimulate the growth promoting effects while also promoting cell migration and has a length of 259 amino acids and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including protein-energy malnutrition, pre-eclampsia, persistent fetal circulation syndrome, Silver-Russell syndrome, growth hormone deficiency, Ehlers-Danlos syndrome, glucose intolerance, Prader-Willi syndrome, and chronic fatigue syndrome. IGFBP1 has also been shown to have interactions with IGF1, IGF2, MMP26, TF, and ARNT in pathways such as the myometrial relaxation and contraction, HIF-1-alpha transcription factor, IGF regulation, and protein metabolism pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

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Publications for IGFBP-1 Recombinant Protein (P4127) (0)

There are no publications for IGFBP-1 Recombinant Protein (P4127).
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FAQs for IGFBP-1 Recombinant Protein (P4127). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in purchasing one of your IGFBP1 protein. I located 3 products from your website, can you please check for me if cat no. NBP1-99680 is a native protein?
    • Both NBP1-99680 and P4127 are biologically active and can be considered to be the native protein.

Additional IGFBP-1 Products

Research Areas for IGFBP-1 Recombinant Protein (P4127)

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Blogs on IGFBP-1.

Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysis
By Rosa Moreno, PhD. Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysisPhysiological low levels of oxygen induce normal hypoxic events across biological systems. This hypoxic state activ...  Read full blog post.

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Bioinformatics

Gene Symbol IGFBP1