HSD3B1 Antibody (FDO66Q) 0.1 ml Trophoblast-associated Marker

HSD3B1 NB110-78644

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  • HSD3B1 Primary Antibodies
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  • 4 Publications
  • Alternate Names
     
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Ordering Information: NB110-78644

Catalog NumberNB110-78644
  • FormUnconjugated
  • Formats
  • Size(s)
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HSD3B1 Antibody (FDO66Q) Summary

 
Species Human, Rat, Baboon, Bovine, Primate
Tested Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P
Clonality Monoclonal
Host Mouse
Gene HSD3B1
Purity Protein G purified
Guarantee Plus All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
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HSD3B1 Antibody (FDO66Q) Details

 
Clone FDO66Q
Isotype IgG1
Marker Trophoblast-associated Marker
Immunogen JEG Choriocarcinoma cells
Localization Membrane

Species Reactivity

 
Human, baboon, bovine, rat and marmoset.
Publications Read 2 using NB110-78644 in the following species:
 

Applications/Dilutions

 
Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence 10-20 ug/ml
  • Immunohistochemistry 10-20 ug/ml
  • Immunohistochemistry-Frozen 10-20 ug/ml
  • Immunohistochemistry-Paraffin 10-20 ug/ml
Application Notes

This HSD3B1 antibody is useful for Immunocytochemistry/Immunofluorescence and Immunohistochemistry on paraffin-embedded sections and frozen sections. There has been negative feedback with the use of this antibody in Western blot.

Positive Controls

2 Positive Controls

Other Available
Formats
7C Labeled NB110-78644V2
Alexa Fluor (R) 405 Labeled NB110-78644AF405
Alexa Fluor (R) 488 Labeled NB110-78644AF488
Alexa Fluor (R) 647 Labeled NB110-78644AF647
Alexa Fluor (R) 700 Labeled NB110-78644AF700
Allophycocyanin Labeled NB110-78644APC
Biotin Labeled NB110-78644B
DyLight 350 Labeled NB110-78644UV
DyLight 405 Labeled NB110-78644V
DyLight 405LS Labeled NB110-78644V3
DyLight 488 Labeled NB110-78644G
DyLight 550 Labeled NB110-78644R
DyLight 650 Labeled NB110-78644C
DyLight 680 Labeled NB110-78644FR
DyLight 755 Labeled NB110-78644IR
FITC Labeled NB110-78644F
HRP Labeled NB110-78644H
PE Labeled NB110-78644PE
PerCP Labeled NB110-78644PCP
Learn about Custom Antibody Labeling
Publications
Read 3 publications using
NB110-78644 in the following applications:
  • WB3publications

Product PDFs

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Publications

HSD3B1 Antibody (NB110-78644) has been mentioned in at least 4 publications.
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Protocols and FAQs

Controls & Support Products

Research Tools

View all HSD3B1 Research Tools.

Packaging, Storage & Formulations

 
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer Tris-glycine, 150 mM NaCl
Unit Size 0.1 ml (also available in 0.025 ml (sample size))
Concentration 1 mg/ml
Preservative 0.05% Sodium Azide
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

 
Gene Symbol HSD3B1
Entrez

Alternate Names for HSD3B1

 
  • EC 1.1.1
  • 3BETAHSD
  • 3BH
  • 3-beta-hydroxy-Delta(5)-steroid dehydrogenase
  • steroid Delta-isomerase
  • short chain dehydrogenase/reductase family 11E, member 1,3-beta-hydroxy-5-ene steroid dehydrogenase
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
  • progesterone reductase
  • HSDB3A
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1
  • 3-beta-HSD I
  • delta-5-3-ketosteroid isomerase
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I
  • I
  • Trophoblast antigen FDO161G
  • HSDB3
  • SDR11E1
  • HSD3B
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

Related Products by Gene

Background

 
3A-hydroxysteroid dehydrogenase (HSD3B) is a bifunctional enzyme from 3-beta-HSD family that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid as well as ketosteroids, and is essential for the biosynthesis of all classes of hormonal steroids. HSD3B catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosteron. HSD3B is highly expressed in placenta, skin, mammary tissues etc and localize to ER/mitochondrion membranes as single-pass membrane protein wherein it plays critical role in lipid metabolism as well as steroid biosynthesis pathways. Among its different isoforms, HSD3B1 is abundantly expressed in human placenta and is implicated progesterone biosynthesis for the maintenance of pregnancy. HSD3B1 polymorphism has been linked to prostate cancer susceptibility, an increased risk of benign prostate hyperplasia, and essential hypertension.