HNF-4 alpha/NR2A1 Antibody (EPR3648) Summary
| Immunogen |
A synthetic peptide corresponding to residues in human HNF4 Alpha was used as an immunogen. |
| Isotype |
IgG |
| Clonality |
Monoclonal |
| Host |
Rabbit |
| Gene |
HNF4A |
| Purity |
Tissue culture supernatant |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Flow Cytometry 1:10-100
- Immunocytochemistry/ Immunofluorescence 1:100-250
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:100-250
- Immunoprecipitation 1:10-100
- Western Blot 1:1000-10000
|
| Application Notes |
This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 52kDa. |
Reactivity Notes
Reacts with: Human Does not react with Mouse, Rat
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
49% PBS, 0.05% BSA and 50% Glycerol |
| Preservative |
0.01% Sodium Azide |
| Purity |
Tissue culture supernatant |
Notes
Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Alternate Names for HNF-4 alpha/NR2A1 Antibody (EPR3648)
Background
The protein encoded by the HNF4 gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. At least three different transcript variants encoding three different isoforms have been found for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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