HDAC6 Antibody (NB120-12173)
HDAC6 Antibody
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Distributor Data...
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anti-HD6 antibody, anti-JM21 antibody, anti-HDAC 6 antibody |
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HDAC6 Antibody Summary: | | Gene: | HDAC6 |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional HDAC6 Products HDAC6 Antibody Details: | Isotype: | IgG |
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| Immunogen: | Synthetic peptide: KNIAHQNKFGEDMPH conjugated to KLH, corresponding to amino acids 1199-1213 of Human HDAC6. |
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| Localization: | Cytoplasmic and Nuclear |
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Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Uses: | IP: Use at an assay dependent dilution. WB: Detects a band of approximately 134 kDa. Additional non-specific bands of approx. 50 kDa may be detected in various extract preparations. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
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| Dilutions: | immunoprecipitation ,
Western Blot 1:1000 |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Phosphate buffered saline |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
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Reviews (1) Related Products (28) Exploring HDAC6 Working with HDAC6
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Jump to: Publications, Reviews, Ask a Question
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Working with HDAC6
HDAC6 Antibody Images (0)
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Reviewed by:
Yuan-Ming Hsu 12/30/2011
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Application:
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Western Blot
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Sample Tested:
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Human
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Species:
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Human
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Dilution Ratio:
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1:1000
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Incubation Time:
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Overnight
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Incubation Temperature:
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4
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Description:
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Anti-Rabbit IgG HRP
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Dilution Ratio:
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1:5000
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Method:
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ECL Plus
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Additional Comments:
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Good antibody.
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Publications (3)
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| HDAC6 Lysate | NBL1-11484 | | WB | (1) | | | | Other Positive Controls- 293T cells expressing recombinant mouse HDAC6.
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Lysates (2)Peptides and ProteinsPrimary Antibodies (20)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| HDAC6 Antibody | NBP1-78981 | Hu | ICC, IF, IHC (-), WB (-) | (1) | | | | | HDAC6 Antibody | NBP1-82212 | Hu | IF, IHC-P, WB | (3) | | | | | HDAC6 Antibody | NB100-91805 | Hu, Mu, Rt | ELISA, IF, IHC-P, WB | (2) | (1) | | | | HDAC6 Antibody | NBP1-61625 | Hu, Mu | ELISA, IF, IHC, WB | (3) | | | | | HDAC6 Antibody (EPR1698(2)) | NBP1-95761 | Hu | ICC, IHC-P, IP, WB | (2) | | | | | ... and 15 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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