Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 1165 and 1215 of human histone deacetylase 6 using the numbering given in entry NP_006035.2 (GeneID 10013).
Species Reactivity:
Human.
Applications:
Uses:
This antibody is useful for Western Blot and Immunoprecipitation
Dilutions:
immunoprecipitation 2-5 ug/mg lysate,
Western Blot 1:2000-1:10000
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Western Blot and Immunoprecipitation: HDAC6 Antibody [NB100-61065] - Detection of Human HDAC6 on HeLa whole cell lysate using NB100-61065. HDAC6 was also immunoprecipitated by rabbit anti-HDAC6 antibody NB100-61064.