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48 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NBP1-67592 in the following applications:
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified
Alternate Names for HDAC3 Antibody
EC 3.5.1.98
HD3RPD3-2RPD3
HDAC3
Histone Deacetylase 3
KDAC3
RPD3-2
SMAP45
Background
HDAC3 is a 50 kD class I histone deacetylase similar to yeast RPD3 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC3 is modified by phosphorylation and sumoylation. HDAC3 has been reported to interact with HDAC4, SMRT and N-CoR co-repressors, GATA-2 and TF-II-I. The Poly6076 antibody has been shown to be useful for Western blotting and immunofluorescence detection of human HDAC3. Interacts with HDAC4, SMRT and N-CoR co-repressors, GATA-2, and TF-II-I
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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