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HDAC3 Antibody (Y415)

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Product Details

Summary
Product Discontinued
View other related HDAC3 Primary Antibodies

Order Details


    • Catalog Number
      NB110-57033
    • Availability
      Product Discontinued

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HDAC3 Antibody (Y415) Summary

Immunogen
A synthetic peptide corresponding to residues in the C-term of human Histone deacetylase 3 was used as immunogen.
Specificity
This antibody may detect splice isoform 2 (RPD3-2A).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HDAC3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:250-500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:250-500
  • Immunoprecipitation 1:50
  • Western Blot 1:5000-10000
Application Notes
This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 49kDa.
Theoretical MW
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
HDAC3 Overexpression Lysate
Publications
Read Publications using
NB110-57033 in the following applications:

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Protein A purified

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for HDAC3 Antibody (Y415)

  • EC 3.5.1.98
  • HD3RPD3-2RPD3
  • HDAC3
  • Histone Deacetylase 3
  • KDAC3
  • RPD3-2
  • SMAP45

Background

Histone deacetylase 3 belongs to the histone deacetylase family type 1 which actively deacetylate Histones. Currently 3 known isoforms exists (HDAC3, HDAC3A and HDAC3C) (1). HDAC3 represses transcription and binds transcription factor YY1 to form a large complex. N-Cor binds HDAC3 in a different manner than other HDACs. In addition to N-Cor, HDAC3 will form a complex with corepressor SMRT (2). HDAC3 is also known to interact with DAXX, HDAC10 and DACH1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HDAC3 Antibody (NB110-57033)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Filter By Species
Human
(1)
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Product General Protocols

View specific protocols for HDAC3 Antibody (NB110-57033): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HDAC3 Antibody (NB110-57033) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional HDAC3 Products

Research Areas for HDAC3 Antibody (NB110-57033)

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Bioinformatics

Gene Symbol HDAC3
Entrez
Uniprot