Novus Biologicals, LLC
PO Box 802; Littleton, CO, 80160 USA
Phone: 303.730.1950 Fax: 303.730.1966
ACTL7A Antibody (H00010881-B01)
ACTL7A Antibody
| Catalog#: | H00010881-B01 |
This product is fully covered under guarantee+ |
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| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
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| Buffer: | This antibody is in antisera and the concentration is unavailable. |
| Preservative: | No Preservative |
| Purity: | Whole antisera |
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| Host: | Mu |
| Clonality: | Polyclonal |
| Specificity: | ACTL7A - actin-like 7A, |
| Modification: | No |
| Immunogen: | ACTL7A (1 a.a. ~ 435 a.a) full-length human protein. |
| Epitope: | MWAPPAAIMGDGPTKKVGNQAPLQTQ ALQTASLRDGPAKRAVWVRHTSSEPQ EPTESKAAKERPKQEVTKAVVVDLGT GYCKCGFAGLPRPTHKISTTVGKPYM ETAKTGDNRKETFVGQELNNTNVHLK LVNPLRHGIIVDWDTVQDIWEYLFRQ EMKIAPEEHAVLVSDPPLSPHTNREK YAEMLFEAFNTPAMHIAYQSRLSMYS YGRTSGLVVEVGHGVSYVVPIYEGYP LPSITGRLDYAGSDLTAYLLG |
| Entrez: | 10881 (Human) |
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| Related Genes: | 10881 |
| Swiss Prot: | NP_006678.1 (Human) |
Background:
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
| Hu | |
| reactivity: | Human. Other species not tested.. |
| ELISA, WB | |
| Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. |
| Dilutions: | Western Blot 1:500, ELISA |
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Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
ACTL7A in Context
