ACTL7A Antibody

Protein Type: Full length Protein Species: Hu Applications: ELISA, WB Clonality: Polyclonal	Gene: ACTL7A Purity: Whole antisera Host: Mouse
Specificity: ACTL7A - actin-like 7A,
See All ACTL7A Products See All ACTL7A Related Products: Lysates Peptides and Proteins Primary Antibodies
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Immunogen:	ACTL7A (1 a.a. ~ 435 a.a) full-length human protein.
Epitope:	MWAPPAAIMGDGPTKKVGNQAPLQTQ ALQTASLRDGPAKRAVWVRHTSSEPQ EPTESKAAKERPKQEVTKAVVVDLGT GYCKCGFAGLPRPTHKISTTVGKPYM ETAKTGDNRKETFVGQELNNTNVHLK LVNPLRHGIIVDWDTVQDIWEYLFRQ EMKIAPEEHAVLVSDPPLSPHTNREK YAEMLFEAFNTPAMHIAYQSRLSMYS YGRTSGLVVEVGHGVSYVVPIYEGYP LPSITGRLDYAGSDLTAYLLG

Entrez:	10881 (Human)
Swiss Prot:	NP_006678.1 (Human)
Related Genes:	ACTL7B, CTNNAL1

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.

Reactivity:	Human. Other species not tested.

Uses:	Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
Dilutions:	Western Blot 1:500, ELISA

This product is produced by and distributed for Abnova, a company based in Taiwan.

Buffer:	This antibody is in antisera and the concentration is unavailable.
Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.