ACTR1A Antibody

Protein Type: Full length Protein Species: Hu Applications: WB, ELISA Clonality: Polyclonal

Gene: ACTR1A Purity: Whole antisera Host: Mouse

Specificity:	ACTR1A - ARP1 actin-related protein 1 homolog A, centractin alpha (yeast),

Immunogen:	ACTR1A (-, 1 a.a. ~ 376 a.a) full-length human protein.
Epitope:	MESYDVIANQPVVIDNGSGVIKAGFA GDQIPKYCFPNYVGRPKHVRVMAGAL EGDIFIGPKAEEHRGLLSIRYPMEHG IVKDWNDMERIWQYVYSKDQLQTFSE EHPVLLTEAPLNPRKNRERAAEVFFE TFNVPALFISMQAVLSLYATGRTTGV VLDSGDGVTHAVPIYEGFAMPHSIMR IDIAGRDVSRFLRLYLRKEGYDFHSS SEFEIVKAIKERACYLSINPQKDETL ETEKAQYYLPDGSTIEIGPSR

Entrez:	10121 (Human)
Swiss Prot:	NP_005727.1 (Human)
Related Genes:	ACTL6B, DCTN1, NR2F1, NR2F2, NR2F2, ABL1, AKAP5, ANPEP, CHAF1A, ANPEP, NR2F2, RAB3GAP2, CTR9, PIK3R4, ARFRP1, ANGPTL2, NR2F1, ACTR2, ACTR2, ANGPTL2, ACTR2, ACTR3B, AICDA, AICDA, RERE, CRISP1, RERE, RERE, MANF, VCSA1, ANGPTL6, DCTN2, SQSTM1, NUP62, KHDRBS1, GTF2H1, KHDRBS1, DCTN4, SQSTM1, IGF2BP2

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Reactivity:	Human.

Uses:	Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for ELISA.
Dilutions:	ELISA, Western Blot 1:500

This product is produced by and distributed for Abnova, a company based in Taiwan.

Buffer:	This antibody is in antisera and the concentration is unavailable.
Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.