ACTR1A Antibody

Protein Type: Full length Protein Species: Hu Applications: WB, ELISA Clonality: Polyclonal	Gene: ACTR1A Purity: Whole antisera Host: Mouse
Specificity: ACTR1A - ARP1 actin-related protein 1 homolog A, centractin alpha (yeast),
See All ACTR1A Products See All ACTR1A Related Products: Lysates Peptides and Proteins Primary Antibodies RNAi
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Immunogen:	ACTR1A (-, 1 a.a. ~ 376 a.a) full-length human protein.
Epitope:	MESYDVIANQPVVIDNGSGVIKAGFA GDQIPKYCFPNYVGRPKHVRVMAGAL EGDIFIGPKAEEHRGLLSIRYPMEHG IVKDWNDMERIWQYVYSKDQLQTFSE EHPVLLTEAPLNPRKNRERAAEVFFE TFNVPALFISMQAVLSLYATGRTTGV VLDSGDGVTHAVPIYEGFAMPHSIMR IDIAGRDVSRFLRLYLRKEGYDFHSS SEFEIVKAIKERACYLSINPQKDETL ETEKAQYYLPDGSTIEIGPSR

Entrez:	10121 (Human)
Swiss Prot:	NP_005727.1 (Human)
Related Genes:	NR2F2, DCTN1, ARFRP1, IKBKAP, ABL1, CHAF1A, PIK3R4, ANPEP, CTR9, RAB3GAP2, AKAP5, NR2F1, ANGPTL1, APOBEC2, BACE2, ANGPTL2, ACTR2, AICDA, KAP, SQSTM1, NUP62, CRISP1, AKR1B10, KHDRBS1, VCSA1, IGF2BP2, GTF2H1, MANF, RERE, DCTN4, ANGPTL4, APOBEC3B, ACTL6A, ACTR3, ACTR1B, TPPP, ACTB, CD40, LSP1, ARHGEF7

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Reactivity:	Human.

Uses:	Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for ELISA.
Dilutions:	ELISA, Western Blot 1:500

This product is produced by and distributed for Abnova, a company based in Taiwan.

Buffer:	This antibody is in antisera and the concentration is unavailable.
Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.