Novus Biologicals, LLC
PO Box 802; Littleton, CO, 80160 USA
Phone: 303.730.1950 Fax: 303.730.1966
ADAM15 Antibody (H00008751-B01)
ADAM15 Antibody
| Catalog#: | H00008751-B01 |
This product is fully covered under guarantee+ |
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| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
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| Buffer: | This antibody is in antisera and the concentration is unavailable. |
| Preservative: | No Preservative |
| Purity: | Whole antisera |
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| Host: | Mu |
| Clonality: | Polyclonal |
| Specificity: | ADAM15 - ADAM metallopeptidase domain 15 (metargidin), |
| Modification: | No |
| Immunogen: | ADAM15 (-, 1 a.a. ~ 772 a.a) full-length human protein. |
| Epitope: | MRLALLWALGLLGAGSPLPSWPLPNI GGTEEQQAESEKAPREPLEPQVLQDD LPISLKKVLQTSLPEPLRIKLELDGD SHILELLQNRELVPGRPTLVWYQPDG TRVVSEGHTLENCCYQGRVRGYAGSW VSICTCSGLRGLVVLTPERSYTLEQG PGDLQGPPIISRIQDLHLPGHTCALS WRESVHTQKPPEHPLGQRHIRRRRDV VTETKTVELVIVADHSEAQKYRDFQH LLNRTLEVALLLDTFFRPLNV |
| Entrez: | 8751 (Human) |
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| Related Genes: | 8751 |
| Swiss Prot: | NP_997074.1 (Human) |
Background:
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Hu | |
| reactivity: | Human.. |
| ELISA, WB | |
| Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. |
| Dilutions: | Western Blot 1:500, ELISA |
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Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
