BAF53A Antibody (3C4)

Species: Hu Applications: WB, ELISA Clonality: Monoclonal

Gene: ACTL6A Purity: IgG purified Host: Mouse

Specificity:	ACTL6A - actin-like 6A (3C4)

Clone:	3C4
Isotype:	IgG1 Kappa
Immunogen:	ACTL6A (NP_817126, 1 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Epitope:	MVVERDDGSTLMEIDGDKGKQGGPTY YIDTNALRVPRENMEAISPLKNGMVE DWDSFQAILDHTYKMHVKSEASLHPV LM*

Entrez:	86 (Human)
Swiss Prot:	NP_817126 (Human)
Related Genes:	ACTL6B, SMARCA1, SMARCA4, MYST2, ARFRP1, SMARCA4, MYST2, MYST4, RERE, CRISP1, RERE, RERE, MANF, VCSA1, SMARCA2, BANF1, BANF1, BANF1, ACTL6B, KAT5, SMARCA4, ANGPTL4, ANGPTL4, SMARCA2, ACTR6, TRRAP, ACTR6, TRRAP, RUVBL1, SMARCC2, RUVBL2, HIST4H4, RUVBL1, TRRAP, APOBEC3D, ANGPTL6, SMARCC2, RUVBL1, APOBEC2, SMARCE1

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

Reactivity:	Human.

Uses:	Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Dilutions:	ELISA, Western Blot 1:500

This product is produced by and distributed for Abnova, a company based in Taiwan.

Buffer:	In 1x PBS, pH 7.2
Storage:	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.