Novus Biologicals, LLC
PO Box 802; Littleton, CO, 80160 USA
Phone: 303.730.1950 Fax: 303.730.1966
Intra Acrosomal Protein Antibody (H00000056-B01)
Intra Acrosomal Protein Antibody
| Catalog#: | H00000056-B01 |
This product is fully covered under guarantee+ |
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| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
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| Buffer: | This antibody is in antisera and the concentration is unavailable. |
| Preservative: | No Preservative |
| Purity: | Whole antisera |
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| Host: | Mu |
| Clonality: | Polyclonal |
| Specificity: | ACRV1 - acrosomal vesicle protein 1, |
| Modification: | No |
| Immunogen: | ACRV1 (AAH14588, 1 a.a. ~ 266 a.a) full-length human protein. |
| Epitope: | MNRFLLLMSLYLLGPARGTSSQPNEL SGSIDHQTSVQQLPGEFFSLENPSDA EALYETSSGLNTLSEHGSSEHGSSKH TVAEHTSGEHAESEHASGEPAATEHA EGEHTVGEQPSGEQPSGEHLSGEQPL SELESGEQPSDEQPSGEHGSGEQPSG EQASGEQPSGEHASGEQASGAPISST STGTILNCYTCAYMNDQGKCLRGEGT CITQNSQQCMLKKIFEGGKLQFMVQG CENMCPSMNLFSHGTRMQIIC |
| Entrez: | 56 (Human) |
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| Related Genes: | 56 |
| Swiss Prot: | AAH14588 (Human) |
Background:
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
| Hu | |
| reactivity: | Human. Other species not tested.. |
| ELISA, WB | |
| Uses: | Antibody reactive against transfected protein with on ELISA and Western Blot. Untransfected protein used as a negative control. |
| Dilutions: | Western Blot 1:500, ELISA |
| Positive Controls: | Intra Acrosomal Protein Lysate (Intra Acrosomal Protein Lysate (H00000056-T01)(0.1ml)) |
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Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
