Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
A synthetic peptide as a part of human, rat, mouse GABA(A) receptor-associated protein-like 2 (GABARAPL2, ATG8, GEF2, GEF-2, GATE16, GATE-16, FLC3A) conjugated to immunogenic carrier protein has been used as the immunogen.
Species Reactivity:
Human, Mouse and Rat.
Applications:
Uses:
Immunohistochemistry-Paraffin/Frozen and Western Blot
Dilutions:
Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot 1:200 to 1:5000
Unit Size:
0.1 ml
Concentration:
lyoph
Notes:
Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:
Lyophilized
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.; Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.; SUBCELLULAR LOCATION: Golgi apparatus.; TISSUE SPECIFICITY: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.