Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 2462 and 2511 of human fatty acid synthase using the numbering given in entry NP_004095.4 (GeneID 2194).
Species Reactivity:
Human and Mouse.
Applications:
Uses:
This antibody is useful for immunohistochemistry on paraffin sections and immunofluorescence. Epitope exposure with citrate bufferexposure is recommended. Epitope exposure with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq]
Detection of Human FAS by IHC-IF. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- FAS (Cat. No. NB100-87029) used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly crossadsorbed Antibody Hilyte PlusTM 555 used at a dilution of 1:100.
Immunohistochemistry: FAS Antibody [NB100-87029] - Detection of Mouse FAS by Immunohistochemistry. Sample: FFPE section of mouse renal cell carcinoma. Antibody: Affinity purified rabbit anti-FAS (Cat. No. NB100-87029) used at a dilution of 1:250.
Immunohistochemistry: FAS Antibody [NB100-87029] - Detection of Human FAS by Immunohistochemistry. Sample: FFPE section of breast carcinoma. Antibody: Affinity purified rabbit anti-FAS (Cat. No. NB100-87029) used at a dilution of 1:250.