Fas Antibody (NB500-503)
Fas Antibody (LT95)
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Distributor Data...
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anti-ALPS1A antibody, anti-TNFRSF6 antibody, anti-FASTM antibody, anti-FAS1 antibody, anti-CD95 antibody, anti-APT1 antibody, anti-Apo-1 Fas antibody, anti-APO-1 antibody, |
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Fas Antibody (LT95) Summary: | | Gene: | FAS |
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| Purity: | Affinity purified |
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| Host: | Mouse |
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| | Specificity: | Human Fas (CD95/APO-1). |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Fas Products Fas Antibody (LT95) Details: | Clone: | LT95 |
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| Isotype: | IgG1 |
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| Immunogen: | Tissue / cell preparation (Human). (T cell lymphoma cells HUT-78). |
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| Localization: | Type I membrane protein (isoform 1); Secreted (isoforms 2 to 6). |
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Cross-reacts with Human. Not yet tested in other species. |
| Uses: | Flow Cytometry Use at an assay dependant concentration. Does not induce Fas mediated apoptosis in susceptible cells. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
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| Dilutions: | Flow Cytometry,
Immunohistochemistry-Paraffin 1:200 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS [pH 7.4] |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Fas / APO1 (CD95) is an important member of the tumour necrosis factor (TNF) superfamily involved in membrane mediated apoptosis. Ligation of Fas by Fas Ligand or an anti Fas cross linking antibody, triggers activation of the caspase cascade. Functional impairment of the Fas / Fas Ligand system is associated with the development and progression of malignancies. Fas gene mutations have been suggested to have a role in testicular germ cell tumors. Tumor cells frequently exhibit de novo expression of Fas Ligand, which plays a significant role in local tissue destruction, metastatic spread, and immune escape of the tumor cells. The apoptosis of lymphocytes, which occurs in autoimmune diseases, is usually induced by the Fas/Fas Ligand system.
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Images (1) Reviews (0) Related Products (90) Exploring Fas
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Jump to: Images, Ask a Question
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Working with Fas
Fas Antibody (LT95) Images (1) Flow Cytometry: Fas Antibody (LT95) [NB500-503] - Fig. 1. Flow cytometry analysis of Fas (CD95) expression on the surface of various hematopoietic cell lines with purified anti-human CD95 (LT95) (detection by Goat anti-mouse IgG1 PE). Histograms: Red - Isotype mouse IgG1 control staining Black - standard anti-CD95 monoclonal antibody Green - anti-CD95 (LT95) A. JURKAT human peripheral blood T cell leukemia cell line B. RAMOS human Burkitt lymphoma cell line C. CEM human leukemia cell line D. MOLT-4 human acute lymphoblastic T cell leukemia cell line. |
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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Reacts strongly with IM9 and HUT-78 cell lines. Reacts moderately with Raji, Ramos, U266, Jurkat, BJ
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Antibody Pairs (3)Lysates (3)Peptides and ProteinsPrimary Antibodies (52)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Fas Antibody | NBP1-41407 | Mu, Rt | ICC, IF, IHC-Fr, IHC-P, IP, WB | (2) | | | | | Fas Antibody | NBP1-89034 | Hu | IF, IHC-P, WB | (3) | | | | | Fas Antibody (DX3) | NBP1-28536 | Hu | FACS, IHC-Fr, In vitro, IP | (1) | (5) | | | | Fas Antibody (DX2) | NBP1-28532 | Hu | FACS, IHC-Fr, In vitro, IP | (1) | (5) | | | | Fas Antibody | NBP1-49957 | Hu | IP, WB | (1) | | | | | ... and 47 more. See All » |
RNAi (8)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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