Fas Antibody (NBP1-28533)
Fas Antibody (DX2) [FITC]
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anti-ALPS1A antibody, anti-Tumor necrosis factor receptor superfamily member 6 antibody, anti-TNFRSF6 antibody, anti-TNFR6 antibody, anti-TNF receptor superfamily member 6 antibody, anti-FASTM antibody, anti-FASLG receptor antibody, anti-FASL receptor antibody, anti-FAS1 antibody, anti-FAS Antigen antibody, anti-FAS antibody, anti-Fas (TNF receptor superfamily member 6) antibody, anti-CD95 antigen antibody, anti-CD95 antibody, anti-CD 95 antibody, anti-APT1 antibody, anti-Apoptosis mediating surface antigen FAS antibody, anti-Apoptosis APO1 antigen 1 antibody, anti-Apoptosis antigen 1 antibody, anti-APO1 cell surface antigen antibody, anti-Apo 1 antigen antibody, anti-APO 1 antibody, |
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Fas Antibody (DX2) [FITC] Summary: | | Gene: | FAS |
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| Purity: | IgG purified |
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| Host: | Mouse |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Fas Products Fas Antibody (DX2) [FITC] Details: | Conjugate: | FITC |
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| Clone: | DX2 |
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| Isotype: | IgG1 |
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| Immunogen: | Human CD95/Fas/Apo-1 |
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| Uses: | Flow Cytometry, Immunoprecipitation, Immunohistochemistry-Frozen and In vitro assay |
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| Dilutions: | Flow Cytometry 10 uL/10^6 cells, Immunohistochemistry-Frozen, Immunoprecipitation, In vitro assay |
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| Unit Size: | 1.0 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Conjugated Antibodies: | 1 Conjugated Antibodies |
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Notes: Protect conjugated forms from light. Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | 1.0 mL of PBS/NaN3 |
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| Preservative: | Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95. (1-5)
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Images (1) Reviews (0) Related Products (90) Working with Fas
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Jump to: Publications, Images, Ask a Question
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Working with Fas
Fas Antibody (DX2) [FITC] Images (1) Flow cytometry: CD95 Antibody (DX2) [NBP1-28533] - 1 ug/10^6 The Jurkat human lymphoma cell line was stained with mouse anti-human CD95/Fas-FITC, following which large cells were gated and analyzed on a flow cytometer |
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Publications (5)Fas Antibody (DX2) [FITC] Background References:- van Parijs, L., A.K. Abbas. 1996. Curr. Opin. Immunol. 8:355.
- Nagata, S., P. Golstein. 1995. Science 267:3378.
more... - Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD95 Section, Academic Press, New York, p. 363.
- Kishimoto, T., A.E.G. von dern Borne, S.M. Goyert, D.Y. Mason, M. Miyasaka, L. Moretta, K. Okumura, S. Shaw, T.A. Springer, K. Sugamura, H. Zola, eds. 1998. Leukocyte Typing VI: White Cell Differentiation Antigens, Academic Press, New York.
- Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford.
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Jump to: Conjugated Antibodies, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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