Factor VIII Recombinant Protein 2 ug

Factor VIII H00002157-P01

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Ordering Information: H00002157-P01

Catalog NumberH00002157-P01
  • Size(s)2 ug
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Factor VIII Recombinant Protein Summary

 
Species Human
Tested Applications WB, ELISA, PA
Gene F8
Specificity F8 (NP_063916.1, 1 a.a. - 216 a.a.) recombinant protein with a ~26kD N-terminal GST tag.
Guarantee Plus All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.

Factor VIII Recombinant Protein Details

 
Immunogen This protein is not active and should not be used for experiments requiring activity.

Applications/Dilutions

 
Dilutions
  • Western Blot
  • ELISA
  • Protein Array
Application Notes

Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.

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Research Tools

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Notes

 
This product is produced by and distributed for Abnova, a company based in Taiwan.

Packaging, Storage & Formulations

 
Storage Store at -80C. Avoid freeze-thaw cycles.
Formulation 50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Unit Size 2 ug
Concentration Please see the vial label for concentration.
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

 
Gene Symbol F8
Entrez
Uniprot

Alternate Names for Factor VIII

 
  • Procoagulant component
  • Antihemophilic factor
  • factor VIII F8B
  • FVIII
  • coagulation factor VIIIc
  • DXS1253E
  • F8Ccoagulation factor VIII
  • HEMAF8B
  • AHF
  • coagulation factor VIII, procoagulant component

Related Products by Gene

Background

 
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq]