FUS Antibody Summary
Bovine (91%). Backed by our 100% Guarantee
||WB, ICC/IF, IHC, IHC-P
Immunogen affinity purified
All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
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FUS Antibody Details
A genomic peptide made to an N-terminal region of the human FUS protein (within residues 1-150). [Swiss-Prot P35637]
Human and Mouse. Immunogen sequence has 91% identity to bovine.
||Read Publications using NBP1-50623 in the following species:
- Western Blot 1:5000
- Immunocytochemistry/Immunofluorescence 1:150
- Immunohistochemistry 1:250
- Immunohistochemistry-Paraffin 1:250
This FUS antibody is useful for IHC, ICC/IF and WB where a doublet is seen ~70 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Read Publications using
NBP1-50623 in the following applications:
Frequently Purchased Together
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FUS Antibody (NBP1-50623) has been mentioned in at least 2 publications
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Manufactured by Genomic Antibody Technology™. GAT FAQs
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 0.1% BSA, 30% glycerol
0.05% Sodium Azide
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Alternate Names for FUS Antibody
- 75 kDa DNA-pairing protein
- amyotrophic lateral sclerosis 6
- fused in sarcoma
Related Products by Gene
, TRANSLOCATED IN LIPOSARCOMA
The protein originally described as fused in Sarcoma is actually related to a number of different cellular processes and correlated to several diseases. FUS binds DNA as a single or double strand, and acts as a site for transcription factors to recognize. Since FUS is well-documented to be involved in liposarcoma, lipoma and leukaemia, it is believed that when its normal housekeeping functions related to transcription are disrupted, normal cells become cancerous. Interestingly, FUS is also associated with the fatal neuron disorder amyotrophic lateral sclerosis; interruption of its normal RNA-binding functions leads to incorrect cellular localization and leads to pathologies of the neuron. Thus, FUS regulation of cellular functions is a critical component of maintenance of healthy cells.
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Publications for FUS Antibody (NBP1-50623) (2)
Read what people are writing who have used FUS Antibody (NBP1-50623).
We have publications tested in 2 confirmed species: Human, Mouse.
We have publications tested in 2 applications: WB, IHC-P.
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FAQs for FUS (2)
- In the immunohistochemistry paraffin section protocol....the PBS buffer....should it be at certain pH?
- For IHC application, different labs cites the pH of PBS buffer in the range of 7.1 - 7.6 but most commonly used pH is pH 7.4 (this is what we use in our lab). You may use this PBS (pH 7.4) for making permeablization buffer, antibody diluent buffers and for making wash buffer. For more on the protocol that we use in our lab and for IHC-P troubleshooting suggestions, you may visit: IHC-P Protocol and IHC-P Troubleshooting.
- I was wondering what does Format 7C mean as far as anitbodies go?
- 7C is a fluorophore - it is useful for FLOW. The details of the fluor are (A=425, E=500)
Bioinformatics Tool for FUS
Discover related pathways, diseases and genes to FUS. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Diseases for FUS
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Pathways for FUS
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PTMs for FUS
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Blogs on FUS
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Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f... Read full blog post.