Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Synthetic peptide corresponing to the residues surrounding Proline 247 of human FoxO3
Species Reactivity:
Human, Mouse
Applications:
Uses:
This antibody is useful for Western Blot, Immunohistochemistry and Immunofluorescence. Western blot analyzes of FoxO3 (P247) antibody in extracts from COLO205 cells. Immunohistochemistry analyzes of FoxO3 (P247) antibody in paraffin-embedded human breast carcinoma tissue.
Dilutions:
Immunofluorescence 1:50 - 1:200, Immunohistochemistry-Paraffin 1:50 - 1:200, Western Blot 1:500 - 1:1000
Unit Size:
0.1 mg
Concentration:
1.0 mg/ml
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:
Phosphate buffered saline (PBS), approx. pH 7.2.
Preservative:
15mM Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
FOX3 probably functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of the FOXO3 gene with the MLL gene is associated with secondary acute leukemia.