FOXO3A Antibody (NB100-81928) | Novus Biologicals

FOXO3A Antibody (NB100-81928) (0.1 mg)

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	Catalog Number	NB100-81928
	Size(s)	0.1 mg	Price: N/A
	Availability	Discontinued
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	View All FOXO3A Primary Antibodies

anti-FKHRL1P2 antibody, anti-AF6q21 protein antibody, anti-DKFZp781A0677 antibody, anti-forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1 antibody, anti-Forkhead in rhabdomyosarcoma-like 1 antibody, anti-forkhead homolog (rhabdomyosarcoma) like 1 antibody, anti-FOXO2 antibody, anti-forkhead box protein O3 antibody, anti-AF6q21 antibody, anti-FOXO3Aforkhead box O3A antibody, anti-FKHRL1MGC31925 antibody, anti-MGC12739 antibody, anti-forkhead box O3 antibody

FOXO3A Antibody Summary:

Species:	Hu, Mu, Rt	Gene:	FOXO3
Applications:	WB, IHC	Purity:	Immunogen affinity purified
Clonality:	Polyclonal	Host:	Rabbit
Specificity:	FKHRL1 (specific to a.a. 253) detects endogenous levels of total FKHR1 protein.
Publications:	NB100-81928 has at least 1 Background Reference

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FOXO3A Antibody Details:

Isotype:	IgG
Immunogen:	The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR1 around the phosphorylation site of serine 253 (A-V-SP-M-D).

Species Reactivity:

This antibody is reactive against Human, Mouse, Rat

Applications:

Uses:	This antibody is useful for: Western Blot immunohistochemistry
Dilutions:	Western Blot, immunohistochemistry,
Unit Size:	0.1 mg
Concentration:	1.0 mg/ml
Positive Controls:	1 Positive Controls

Packaging:

Storage:	Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Buffer:	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
Preservative:	0.02% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: FOXO3

Entrez:	2309 (Human)
	56484 (Mouse)
	294515 (Rat)
Uniprot:	O43524 (Human)

Related Genes:

Background:

FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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FOXO3A Antibody Images (2)

	Western Blot: FKHRL1 Antibody [NB100-81928] - Western blot analysis of extracts from NIH/3T3 cells using FKHRL1 (Ab-253) antibody (Lane 1 and 2) and FKHRL1 (phospho-Ser253) antibody (Lane 3 and 4).

	Immunohistochemistry: FKHRL1 Antibody [NB100-81928] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FKHRL1 (Ab-253) antibody.

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Publications (1)

FOXO3A Antibody Background References:

Smith WW, et al. (2005) J Cell Biol; 169(2): 331-9. Essafi A, et al. (2005) Oncogene; 24(14): 2317-29. Brunet A, et al. (2001) Mol Cell Biol; 21(3): 952-65. Brunet A, et al. (1999) Cell; 96(6): 857-68.