FOXO3A Antibody (NB100-614)
FOXO3A Antibody
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Distributor Data...
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anti-AF6q21 antibody, anti-Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1 antibody, anti-FKHRL1P2 antibody, anti-FKHRL1 antibody, anti-FKHR2 antibody, anti-DAF16 antibody, |
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FOXO3A Antibody Summary: | | Gene: | FOXO3 |
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| Purity: | Affinity purified |
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| Host: | Rabbit |
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| | Specificity: | NB100-614 is specific for human FOXO3a protein.
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional FOXO3A Products FOXO3A Antibody Details: | Immunogen: | The epitope recognized by this antibody maps to a region between residue 625 and the C-terminus (residue 673) of human Forkhead Box O3a using the numbering given in Swiss-Prot entry O43524 (GeneID 2309). |
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Human. Reactivity with Mouse FOXO3a is expected owing to complete identity of sequence between this ortholog and Human FOXO3a at the site to which the epitope maps. Reactivity with Drosophila melanogaster is not likely. |
| Uses: | Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: 2 to 5 ug/mg lysate Histo/Cytochemistry: not tested *In some cases, the antibody may be diluted further than indicated. |
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| Dilutions: | Immunoprecipitation 2-5 ug/mg lysate, Western Blot 1:5000-1:15000 |
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| TMW: | 71.3 kDa |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The FOXO3 gene is known to promote longevity in animals and has now been discovered to encode a tumor suppressor. The new gene, which was inactivated in two-thirds of patients studied, presents a potent new target for breast cancer. The protein, named Forkhead box class O3 (FOXO3), is associated with better outcomes for breast cancer patients. Conversely, if FOXO3 was inactivated, patients had worse outcomes.
FOXO3 is inactivated in many cancer patients by an enzyme called IKK, which is an oncoprotein.
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Images (1) Reviews (0) Related Products (46) Exploring FOXO3A
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Working with FOXO3A
FOXO3A Antibody Images (1) WB and IP: FOXO3A Antibody [NB100-614] - Detection of Human FOXO3a on HeLa whole cell lysate using NB100-614. FOXO3a was also immunoprecipitated using NB100-613. |
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (39)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| FOXO3A Antibody | NBP1-39764 | Bv, Ca, Ch, Hu, Mk, Mu, Rt, Xp | IHC-P, WB | (1) | | | | | FOXO3a Antibody (EPR1950) | NBP1-95465 | Hu, Mu, Rt | ICC, IF, WB | (2) | | | | | FOXO3A Antibody (EP1949Y) | NB110-56994 | Hu, Mu(-), Rt(-) | ICC, IHC-P, WB | (2) | (3) | | | | FOXO3A Antibody | NB100-613 | Dr(-), Hu | IP, WB | (1) | | | | | FOXO3A Antibody | NBP1-19826 | Hu, Mu | IF, IHC-P, WB | (2) | | | | | ... and 34 more. See All » |
RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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