FOXO3A Antibody (NB100-613)

FOXO3A Antibody

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FOXO3A Antibody Summary:
Species:Dr(-), Hu
Applications:IP, WB
Clonality:Polyclonal
Gene:FOXO3
Purity:Immunogen affinity purified
Host:Rabbit
 
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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FOXO3A Antibody Details:
Immunogen:The epitope recognized by this antibody maps to a region between residues 250 and 300 of human Forkhead Box O3a using the numbering given in Swiss-Prot entry O43524 (GeneID 2309).
Species Reactivity:

Human. Reactivity with Mouse FOXO3a is expected owing to complete identity of sequence between this ortholog and Human FOXO3a at the site to which the epitope maps. Reactivity with Drosophila melanogaster is not likely.

Applications:
Uses:Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: 2 to 5 ug/mg lysate Histo/Cytochemistry: not tested *In some cases, the antibody may be diluted further than indicated.
Dilutions:Western Blot, immunoprecipitation
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Positive Controls:1 Positive Controls
Packaging:
Storage:Store at 4 °C. Do not freeze.
Buffer:Tris-citrate/phosphate buffer, pH 7 to 8
Preservative:0.09% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: FOXO3
Entrez2309 (Human)
Swiss ProtO43524 (Human)
 
Background:

The FOXO3 gene is known to promote longevity in animals and has now been discovered to encode a tumor suppressor. The new gene, which was inactivated in two-thirds of patients studied, presents a potent new target for breast cancer. The protein, named Forkhead box class O3 (FOXO3), is associated with better outcomes for breast cancer patients. Conversely, if FOXO3 was inactivated, patients had worse outcomes. FOXO3 is inactivated in many cancer patients by an enzyme called IKK, which is an oncoprotein.

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Working with FOXO3A

FOXO3A Antibody Images (1)
WB and IP: FOXO3A Antibody [NB100-613] - Detection of Human FOXO3a on HeLa whole cell lysate using NB100-613. FOXO3a was also immunoprecipitated using NB100-614.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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FOXO3A in Context


Research Areas related to FOXO3A (4):
FOXO3A in the News (1):
Novus Explorer for FOXO3A gene

Try our bioinformatic tool that shows the relationships between FOXO3 and other genes, diseases, pathways and post-translational modifications.