ErbB2/HER2 Antibody (EP2324Y) (NBP1-96060)

ErbB2/HER2 Antibody (EP2324Y) (NBP1-96060) (0.1 ml)

Additional Products Available View our ErbB2/HER2 products. Call 303-730-1950 for recommended products	Ordering Information:
	Catalog Number	NBP1-96060
	Size(s)	0.1 ml	Price:
	Availability
Why Choose Novus?	Bulk Quote
	View All ErbB2/HER2 Primary Antibodies

anti-MLN 19 antibody, anti-EC 2.7.10 antibody, anti-Tyrosine kinase-type cell surface receptor HER2 antibody, anti-CD340 antigen antibody, anti-Proto-oncogene Neu antibody, anti-MLN19 antibody, anti-Proto-oncogene c-ErbB-2 antibody, anti-receptor tyrosine-protein kinase erbB-2 antibody, anti-Metastatic lymph node gene 19 protein antibody, anti-neuroblastoma/glioblastoma derived oncogene homolog antibody, anti-v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog) antibody, anti-herstatin antibody, anti-HER-2 antibody, anti-c-erb B2/neu protein antibody, anti-CD340 antibody, anti-NGLTKR1 antibody, anti-NEUHER-2/neu antibody, anti-HER2EC 2.7.10.1 antibody, anti-p185erbB2 antibody, anti-v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian) antibody

ErbB2/HER2 Antibody (EP2324Y) Summary:

Species:	Hu	Gene:	ERBB2
Applications:	WB, ICC, IF, IHC-P	Purity:	Tissue culture supernatant
Clonality:	Monoclonal	Host:	Rabbit
Publications:

View Additional ErbB2/HER2 Products

ELISA Kits	Lysates
Peptides and Proteins	Primary Antibodies
RNAi
» View All ErbB2/HER2 Related Products

ErbB2/HER2 Antibody (EP2324Y) Details:

Clone:	EP2324Y
Immunogen:	A phospho - specific peptide corresponding to residues surrounding tyrosine 877 of human HER2 was used as an immunogen. This antibody detects HER2 phosphorylated at tyrosine 877.

Species Reactivity:

Human.

Applications:

Uses:	This product is useful in Western Blot,Immunohistochemistry,Immunocytochemistry,
Dilutions:	Immunocytochemistry 1:50 - 100, Immunohistochemistry-Paraffin 1:250 - 500, Western Blot 1:500 - 1000, Immunofluorescence
Unit Size:	0.1 ml
Concentration:	This product is unpurified. Concentration is not relevant.

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	Antibody buffer, sodium azide, glycerol, and BSA.
Preservative:	0.01% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: ERBB2

Uniprot:	P04626 (Human)

Related Genes:

Background:

HER2 / ErbB2 is one of the four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases (1). The kinase activity of ErbB2 can be activated without ligand if it is overexpressed, and by association with other ErbB proteins (2). Overexpression of ErbB2 is detected in almost 40% of human breast cancers (3). ErbB2 is one of the major targets for the treatment of breast cancer and other carcinomas. Autophosphorylation did not modulate receptor turnover. A Tyr----Phe substitution of ErbB-2 Tyr-877 homologous to pp60c-src Tyr-416 did not alter ErbB-2 biological and biochemical properties, thus excluding the possibility that phosphorylation of this residue, located in the kinase domain, modulates ErbB-2 gp185 catalytic function (4).

Images (3)



View All Images...

Be the first to review this product for a reward!

Review this product now.

ErbB2/HER2 Antibody (EP2324Y) Images (3)

	Western Blot: ErbB 2 Antibody (EP2324Y) [NBP1-96060] - 3 using anti-Phospho-HER2 (pY877) (Cat. #2521-1) Cells were either (A,C) untreated (B,D) treated with EGF

	Immunohistochemistry-Paraffin: ErbB 2 Antibody (EP2324Y) [NBP1-96060] - HER2 Phospho (pY877). Note positive (3+) membrane staining of tumor cells

	Immunofluorescence: ErbB 2 Antibody (EP2324Y) [NBP1-96060] SKBR3 cells using anti-HER2 Phospho (pY877) .