ERK2 Antibody (NB110-60506)
ERK2 Antibody (4C11C11C4)
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ERK2 Antibody (4C11C11C4) Summary: | | Gene: | MAPK1 |
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| Purity: | Protein A purified |
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| Host: | Mouse |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional ERK2 Products ERK2 Antibody (4C11C11C4) Details: | Clone: | 4C11C11C4 |
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| Isotype: | IgG2a |
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| Immunogen: | Ni-NTA purified full length recombinant ERK2 expressed in E. Coli strain BL21 (DE3) |
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| Uses: | ELISA, Western Blot and Immunohistochemistry Paraffin and Frozen |
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| Dilutions: | ELISA 1:10000,
Western Blot 1:500-1: 2000,
Immunohistochemistry-Paraffin 1:500-1: 2000,
Immunohistochemistry-Frozen 1:500-1:2000 |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS |
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| Preservative: | 0.03% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.
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Images (3) Reviews (0) Related Products (49) Exploring ERK2 Working with ERK2
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Jump to: Publications, Images, Ask a Question
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Working with ERK2
ERK2 Antibody (4C11C11C4) Images (3)-Immunohistochemistry-Paraffin-NB110-60506-img0003.jpg "Immunohistochemistry-Paraffin: ERK2 Antibody (4C11C11C4) [NB110-60506] - Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and breast carcinoma (right) showing cytoplasmic localization using ERK2 mouse mAb with DAB staining.") Immunohistochemistry-Paraffin: ERK2 Antibody (4C11C11C4) [NB110-60506] - Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and breast carcinoma (right) showing cytoplasmic localization using ERK2 mouse mAb with DAB staining. | -Western Blot-NB110-60506-img0002.jpg "Western Blot: ERK2 Antibody (4C11C11C4) [NB110-60506] - Western blot analysis using ERK2 mouse mAb against Hela (1), NIH/3T3 (2), MCF-7 (3), HEK293 (4), Jurkat (5), A549 (6), NTERA-2 (7) and SMMC-7721 (8) cell lysate.") Western Blot: ERK2 Antibody (4C11C11C4) [NB110-60506] - Western blot analysis using ERK2 mouse mAb against Hela (1), NIH/3T3 (2), MCF-7 (3), HEK293 (4), Jurkat (5), A549 (6), NTERA-2 (7) and SMMC-7721 (8) cell lysate. | -Immunofluorescence-NB110-60506-img0001.jpg "Immunofluorescence: ERK2 Antibody (4C11C11C4) [NB110-60506] - Confocal immunofluorescence analysis of Eca-109 cells using ERK2 mouse mAb (green).") Immunofluorescence: ERK2 Antibody (4C11C11C4) [NB110-60506] - Confocal immunofluorescence analysis of Eca-109 cells using ERK2 mouse mAb (green). |
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Publications (2)ERK2 Antibody (4C11C11C4) Background References:- N Hatano, Y Mori, M Oh-hora Genes Cells, Nov 2003; 8:847- 856.
- Angelique W. Whitehurst, Fred L. Robinson, Mary Shannon Moore J. Biol. Chem., Mar 2004; 279: 12840 - 12847
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (2)Peptides and ProteinsPrimary Antibodies (27)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| ERK2 Antibody (9E9) | NBP1-47846 | Hu, Rt | IHC-P, WB | (10) | | | | | ERK2 Antibody (6E5) | NBP1-47842 | Ca, Hu, Mk, Rt | IHC-P, WB | (8) | | | | | ERK2 Antibody (9H1) | NBP1-47845 | Ca, Hu, Mk, Rt | IHC-P, WB | (6) | | | | | ERK2 Antibody (4C2) | NBP1-47850 | Ca, Hu, Mk, Rt | IF, IHC-P, WB | (4) | | | | | ERK2 Antibody (E460) | NB110-57174 | Hu, Mu, Rt | FACS, ICC, IHC-P, IP, WB | (2) | (2) | | | | ... and 22 more. See All » |
RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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