Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 329 and 379 of human extracellular signal-related kinase 1 (mitogen-activated protein kinase 3) using the numbering given in entry NP_002737.2 (GeneID 5595).
Species Reactivity:
Human
Applications:
Uses:
This antibody is useful for western blot and immunoprecipitation.
Dilutions:
Western Blot 1:2000-1:10000,
immunoprecipitation 2-5 mcg/mg lysate,
Unit Size:
0.1 ml
Concentration:
0.2 mg/ml
Packaging:
Storage:
Store at 4 °C. Do not freeze.
Buffer:
Tris-buffered Saline containing 0.1% BSA
Preservative:
0.09% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq]