Dtk/TYRO3 Antibody 0.1 ml

Click image to view larger
Western Blot: TYRO3 Antibody [NBP1-28635] - Lane 1: Western blot on normal human brain, Lane 2: Western blot on normal mouse brain.
Immunocytochemistry/Immunofluorescence: TYRO3 Antibody [NBP1-28635] - ICC staining of HELA cells using NBP128635 (Green) at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit secondary antibody. Nuclei were visualized using Hoechst 33258 (Blue).
Download Datasheet
See All Related

Ordering Information: NBP1-28635

  • Catalog Number
    NBP1-28635
  • Displayed Format
    Unconjugated
  • Other Formats
  • Size(s)
  • Availability
  • Price
    Shipping
  

Dtk/TYRO3 Antibody Summary

Species Human, Mouse
Predicted Species
Rat (94%). Backed by our 100% Guarantee
Tested Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Gene
TYRO3
Purity
Immunogen affinity purified
Guarantee Plus
All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Dtk/TYRO3 Antibody Details

Immunogen
Synthetic peptide made to an internal portion of the human TYRO3 protein (within residues 100-250). [Swiss-Prot# Q06418]
Localization
Cell membrane; Single-pass type I membrane protein.

Species Reactivity

Human and mouse. Immunogen sequence has 94% identity to rat.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:200
Application Notes
This TYRO3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band can be seen at ~96 kDa.
Molecular Weight
96 kDa
Positive Controls
Other Available
Formats
Alexa Fluor (R) 405 Labeled NBP1-28635AF405
Alexa Fluor (R) 488 Labeled NBP1-28635AF488
Alexa Fluor (R) 647 Labeled NBP1-28635AF647
Alexa Fluor (R) 700 Labeled NBP1-28635AF700
Biotin Labeled NBP1-28635B
DyLight 405 Labeled NBP1-28635V
DyLight 488 Labeled NBP1-28635G
DyLight 550 Labeled NBP1-28635R
DyLight 650 Labeled NBP1-28635C
FITC Labeled NBP1-28635F
HRP Labeled NBP1-28635H
Control Peptide
Dtk/TYRO3 Peptide (NBP1-28635PEP)

Contact Information

Product PDFs

Frequently Purchased Together

Reviews

Earn rewards points by submitting your review for Dtk/TYRO3 Antibody (NBP1-28635). Be the first to review this product and earn double rewards points!

Publications

Earn rewards if you have published using Dtk/TYRO3 Antibody (NBP1-28635).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 30% glycerol
Unit Size
0.1 ml
Concentration
1.29 mg/ml
Preservative
0.1% Sodium Azide
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

Gene Symbol TYRO3
Entrez
Uniprot

Alternate Names for Dtk/TYRO3 Antibody

  • Brt
  • BYK
  • Dtk
  • DTK
  • EC 2.7.10
  • EC 2.7.10.1
  • FLJ16467
  • RSE
  • SKY
  • Sky
  • Tif
  • TYRO3 protein tyrosine kinase
  • Tyrosine-protein kinase byk
  • Tyrosine-protein kinase DTK
  • tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase RSE
  • Tyrosine-protein kinase SKY
Show More

Related Products by Gene

Background

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a RTK which facilitate transduction of signals from extracellular matrix (ECM) into cytoplasm via its direct interaction with multiple ligands such as TUB, TULP1 or GAS6 for the regulation of multiple biological processes such as cell survival, migration and differentiation. TYRO3-ligand binding stimulates its dimerization as well as autophosphorylation on its intracellular domain that provides docking sites for the molecules of downstream signaling. Once stimulated, TYRO3 interacts with PIK3R1 leading to increased PI3K activity followed by AKT signaling activation including NFkB nuclear translocation mediated up-regulation of transcription of NFkB's target genes. TYRO3 signaling events are critical to neuron protection from excitotoxic injury, platelet aggregation, cytoskeletal reorganization, inhibition of TLRs-mediated innate immune response via STAT1 activation followed by production of cytokine signaling suppressors (SOCS1 and SOCS3). TYRO3 is highly expressed during CNS neurogenesis with distinct patterns in adult brain and has been closely related to CNS immunodysfunction.

Reviews for Dtk/TYRO3 Antibody (NBP1-28635) (0)

There are no reviews for Dtk/TYRO3 Antibody (NBP1-28635).
By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image
Have you used Dtk/TYRO3 Antibody (NBP1-28635)? Submit your review and earn rewards points which can be used for merchandise & discounts.
Points can be redeemed for discounts and gift cards:
$50/€35/£30/$50CAN Amazon Gift Card1000 Points
Items ships for Free, please disregard any shipping charges.
$50/€35/£30/$50CAN Off Purchase (credited after checkout)1000 Points
Discount is removed from total when the order is processed. The discount will not appear in your shopping cart on check out.

Publications for Dtk/TYRO3 Antibody (NBP1-28635) (0)

There are no publications for Dtk/TYRO3 Antibody (NBP1-28635).
By submitting a publication earn 200 points for your submission points towards our Rewards Program.
Have you published using Dtk/TYRO3 Antibody (NBP1-28635)? Earn rewards points which can be used for merchandise & discounts.
Points can be redeemed for discounts and gift cards:
$50/€35/£30/$50CAN Amazon Gift Card1000 Points
Items ships for Free, please disregard any shipping charges.
$50/€35/£30/$50CAN Off Purchase (credited after checkout)1000 Points
Discount is removed from total when the order is processed. The discount will not appear in your shopping cart on check out.

Product General Protocols

View specific protocols for Dtk/TYRO3 Antibody (NBP1-28635): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

Ask a Scientist

Submit your question on below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

FAQs for Dtk/TYRO3 (2)

  1. In the immunohistochemistry paraffin section protocol....the PBS buffer....should it be at certain pH?
    • For IHC application, different labs cites the pH of PBS buffer in the range of 7.1 - 7.6 but most commonly used pH is pH 7.4 (this is what we use in our lab). You may use this PBS (pH 7.4) for making permeablization buffer, antibody diluent buffers and for making wash buffer. For more on the protocol that we use in our lab and for IHC-P troubleshooting suggestions, you may visit: IHC-P Protocol and IHC-P Troubleshooting.
  2. I was wondering what does Format 7C mean as far as anitbodies go?
    • 7C is a fluorophore - it is useful for FLOW. The details of the fluor are (A=425, E=500)