This product is specific for Human DRD1 (Dopamine D1). Unless other species reactivities are specified there is no testing data currently available.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The immunogen for this antibody is DRD1 (Dopamine D1) taken from a synthetic peptide [KLH conjugated] made to the 2nd extracellular loop of human source. The exact immunogenic sequence is proprietary.
Species Reactivity:
This antibody is reactive against Human.
Applications:
Uses:
This product is useful for Immunohistochemistry-Paraffin
Dilutions:
Immunohistochemistry-Paraffin
Unit Size:
0.05 ml
Concentration:
1.0 mg/ml
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -80 °C long term. Avoid freeze-thaw cycles.
Buffer:
Phosphate buffered saline, PH 7.7
Preservative:
0.1% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.