Dopamine Receptor D1 Antibody (NB110-60017)
Dopamine Receptor D1 Antibody (SG2-D1a)
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anti-DRD1 antibody, anti-D(1A) dopamine receptor antibody, anti-DRD1A antibody, anti-Drd1 antibody, anti-DRD 1 antibody, anti-DR D1A antibody, anti-DR D1 antibody, anti-Dopamine Receptor D1 antibody, anti-DADR antibody, anti-D1A dopamine receptor antibody, |
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Dopamine Receptor D1 Antibody (SG2-D1a) Summary: | Species: | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) |
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| Applications: | ICC, IF, IHC, WB |
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| Clonality: | Monoclonal |
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| | Gene: | DRD1 |
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| Purity: | Protein A purified |
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| Host: | Mouse |
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| | Specificity: | This reacts with Dopamine Receptor D1A. There is no cross- reactivity with D1B (D5) receptor. |
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| Publications: | Antibody has been mentioned in at least 2 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Dopamine Receptor D1 Products Dopamine Receptor D1 Antibody (SG2-D1a) Details: | Clone: | SG2-D1a |
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| Isotype: | IgG2b Kappa |
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| Immunogen: | Recombinant rat D1 (D1a) dopamine receptor protein near the C-terminus. [Swiss-Prot# P18901]
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| Localization: | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note: Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. |
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| Epitope: | This antibody has not been epitope mapped.
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This antibody reacts with mouse and rat protein. It does not react with human, dog, pig, sheep, rabbit, or cow proteins. Other species have not been tested. |
| Uses: | This antibody is useful for Western Blot analysis, where multiple bands are seen around 45 and 100 kDa (dimer) in sf9 cell lysates overexpressing D1a and a single band at 90 kDa in striatal tissue lysate. Do NOT boil samples. Immunocytochemistry and immunofluorescence have been useful using other productions of this antibody. |
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| Dilutions: | Immunocytochemistry, immunofluorescence, immunohistochemistry, Western Blot |
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| Unit Size: | 0.1 ml (also available: 0.025 ml (sample size)) |
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| Concentration: | 1.4 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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| Conjugated Antibodies: | 5 Conjugated Antibodies |
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Packaging: | Storage: | Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | Tris-glycine, 150mM NaCl |
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| Preservative: | 0.05% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
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Images (1) Reviews (1) Related Products (16) Exploring Dopamine Receptor D1 Working with Dopamine Receptor D1
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Jump to: Publications, Images, Reviews, Protocols/Procedures, Ask a Question
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Working with Dopamine Receptor D1
Dopamine Receptor D1 Antibody (SG2-D1a) Images (1) Detection of Dopamine Receptor D1b of Sf9 cells transfected with rat D1a using NB110-60017. Lane 1: Sf9-D1a lysate. Lane 2: Sf9-D1b lysate (Please note that these results are similiar to those shown in J. Neuroimmunol. 101:170-187 publication.) |
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Reviewed by:
Anonymous 1/18/2010
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Publications (2)
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Jump to: Conjugated Antibodies, Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Dopamine Receptor D1 Antibody (SG2-D1a) [DyLight 488] | NB110-60017G | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) | ICC, IF, WB | | | | | | Dopamine Receptor D1 Antibody (SG2-D1a) [DyLight 550] | NB110-60017R | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) | ICC, IF, WB | | | | | | Dopamine Receptor D1 Antibody (SG2-D1a) [DyLight 650] | NB110-60017C | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) | ICC, IF, WB | | | | | | Dopamine Receptor D1 Antibody (SG2-D1a) [HRP] | NB110-60017H | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) | ICC, IF, WB | | | | | | Dopamine Receptor D1 Antibody (SG2-D1a) [Biotin] | NB110-60017B | Bv(-), Ca(-), Hu(-), Mu, Po(-), Rb(-), Rt, Sh(-) | ICC, IF, WB | | | | |
Positive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Sf9 cell and striatal tissue lysates.
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Lysates (1)Peptides and ProteinsPrimary Antibodies (13)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Dopamine Receptor D1 Antibody (EP1560Y) | NB100-79930 | Hu, Mu, Rt | FACS, WB | (1) | (4) | | | | Dopamine Receptor D1 Antibody | NBP1-87577 | Hu | IF, IHC-P, WB | (1) | | | | | Dopamine Receptor D1 Antibody | NLS44 | Hu | ICC, IHC-P | (2) | | | | | Dopamine Receptor D1 Antibody (SG2-D1a) | MAB2314 | Mu, Rt | ICC, IF, WB | | | | | | Dopamine Receptor D1 Antibody | PAB12318 | Hu, Mu, Rt | WB | | | | | | ... and 8 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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