DAP1 Antibody (NB110-56925)
DAP1 Antibody (E59)
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Distributor Data...
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anti-DAP 1 antibody, anti-MGC99796 antibody, anti-Death Associated Protein 1 antibody, anti-DAP antibody |
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DAP1 Antibody (E59) Summary: | | Gene: | DAP |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional DAP1 Products DAP1 Antibody (E59) Details: | Clone: | E59 |
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| Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to C-terminus of human DAP-1 was used as immunogen. |
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Reacts in Human. Does not react to Mouse or Rat. |
| Uses: | This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 11kDa. |
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| Dilutions: | Western Blot 1:1000-10000, Immunohistochemistry-Paraffin 1:100-1:250, Immunocytochemistry 1:250, Immunoprecipitation 1:50 |
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| TMW: | 11 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Death associated protein 1 (DAP-1) is a 15-kDa protein that functions as a positive mediator of cell death initiated by interferon (IFN-) gamma (1,2). DAP-1 is proline rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites (1). It is localized to the cytoplasm, but the detailed mechanism of its pro-apoptotic function is unclear. DAP-1 and DAP kinase, a unique, 160-kDa calmodulin-dependent serine/threonine kinase, are both unique candidates for positive mediators of programmed cell death induced by IFN-gamma (3).
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Images (3) Reviews (0) Related Products (6) Exploring DAP1 Working with DAP1
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Jump to: Peptides and Proteins, Primary Antibodies, Secondary Antibodies
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![Immunohistochemistry: DAP-1 Antibody (E59) [NB110-56925] - Immunohistochemical analysis of paraffin-embedded human stomach carcinoma using anti-DAP-1 (catalog #110-56925).](http://images.novusbio.com/images/p_56925_2.jpg "Immunohistochemistry: DAP-1 Antibody (E59) [NB110-56925] - Immunohistochemical analysis of paraffin-embedded human stomach carcinoma using anti-DAP-1 (catalog #110-56925).")
![Western Blot: DAP-1 Antibody (E59) [NB110-56925] - Western blot analysis on NIH3T3 cell lysate using anti-DAP-1 (catalog #110-56925), dilution 1:10,000.](http://images.novusbio.com/images/p_56925_1.jpg "Western Blot: DAP-1 Antibody (E59) [NB110-56925] - Western blot analysis on NIH3T3 cell lysate using anti-DAP-1 (catalog #110-56925), dilution 1:10,000.")
![Immunofluorescent: DAP-1 Antibody (E59) [NB110-56925] - Immunofluorescent analysis of HeLa cells using anti-DAP-1 (catalog #110-56925).](http://images.novusbio.com/images/p_56925_3.jpg "Immunofluorescent: DAP-1 Antibody (E59) [NB110-56925] - Immunofluorescent analysis of HeLa cells using anti-DAP-1 (catalog #110-56925).")
