Cdk2 Antibody (NB110-55713)
Cdk2 Antibody (E304)
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Distributor Data...
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anti-CDK2 antibody, anti-p33(CDK2) antibody, anti-p33 protein kinase antibody, anti-Cyclin dependent kinase 2 antibody, anti-Cell division protein kinase 2 antibody, anti-Cell division kinase 2 antibody, anti-Cdk 2 antibody, anti-Cdc2 related protein kinase antibody |
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Cdk2 Antibody (E304) Summary: | | Gene: | CDK2 |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Cdk2 Products Cdk2 Antibody (E304) Details: | Clone: | E304 |
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| Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to residues in C-terminus of human Cdk2 was used as immunogen. |
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Reacts in Human, Mouse, Rat. |
| Uses: | This product is useful for: Western Blot, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 33kDa. |
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| Dilutions: | Western Blot 1:1000-5000, Immunocytochemistry 1:100, Immunoprecipitation 1:40 |
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| TMW: | 33 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Cyclin-dependent protein kinase 2 (Cdk2), also known as cell division protein kinase 2, is a 34-kDa nuclear protein that regulates events within G1 and S phase in the human cell cycle (1-4). Cdk2 is inactive until a complex is formed with cyclin A, D, or E (2). Inhibitory phosphorylation occurs on Thr14 and Tyr15. Activation of the Cdk2 complex requires dephosphorylation of Thr14 and Tyr15 by cdc25 phosphatase and phosphorylation of Thr160, which is mediated by CAK (3,4).
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Images (2) Reviews (0) Related Products (35) Exploring Cdk2 Working with Cdk2
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Jump to: Publications, Images, Ask a Question
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Working with Cdk2
Cdk2 Antibody (E304) Images (2) Western Blot: Cdk2 (C-term) Antibody (E304) [NB110-55713] - Western blot analysis on HeLa cell lysate using anti-Cdk2 (C-term) (NB110-55713); dilution 1:5,000. |  Immunofluorescent: Cdk2 (C-term) Antibody (E304) [NB110-55713] - Immunofluorescent staining of HeLa cells using anti-Cdk2 (C-term) |
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Publications (1)Cdk2 Antibody (E304) Background References:- Morgan, D.O. Principles of CDK regulation. Nature 374: 131
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Jump to: Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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RNAi (3)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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