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CDK2 Antibody (E304)

 (1 Publication)
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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-55713
    • Availability
      Product Discontinued

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CDK2 Antibody (E304) Summary

Immunogen
A synthetic peptide corresponding to residues in C-terminus of human Cdk2 was used as immunogen.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CDK2
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Immunoprecipitation 1:40
  • Western Blot 1:1000-5000
Application Notes
This product is useful for: Western Blot, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 33kDa.
Publications
Read Publication using NB110-55713.

Reactivity Notes

Human, Mouse, Rat. Cross reactivity determined by Western Blot only.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Protein A or G purified

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for CDK2 Antibody (E304)

  • cdc2-related protein kinase
  • CDK2
  • cell devision kinase 2
  • Cell division protein kinase 2
  • cyclin-dependent kinase 2
  • EC 2.7.11
  • EC 2.7.11.22
  • p33 protein kinase
  • p33(CDK2)

Background

Cyclin-dependent protein kinase 2 (Cdk2), also known as cell division protein kinase 2, is a 34-kDa nuclear protein that regulates events within G1 and S phase in the human cell cycle (1-4). Cdk2 is inactive until a complex is formed with cyclin A, D, or E (2). Inhibitory phosphorylation occurs on Thr14 and Tyr15. Activation of the Cdk2 complex requires dephosphorylation of Thr14 and Tyr15 by cdc25 phosphatase and phosphorylation of Thr160, which is mediated by CAK (3,4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CDK2 Antibody (NB110-55713)(1)


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Bioinformatics

Gene Symbol CDK2
Entrez
Uniprot