Carboxyl Methyl Lysine Antibody (NB600-1337)

Carboxyl Methyl Lysine Antibody

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Carboxyl Methyl Lysine Antibody Summary:
Species:All
Applications:ELISA, WB
Clonality:Polyclonal
Purity:Affinity purified
Host:Rabbit
Specificity:This specifically binds to Carboxy methyl Lysine modified proteins.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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Carboxyl Methyl Lysine Antibody Details:
Isotype:IgG
Immunogen:Carboxy methyl Lysine conjugated to KLH.
Species Reactivity:

All Species.

Applications:
Uses:This antibody is useful for ELISA and Western Blot.
Dilutions:ELISA 1/2500 - 1/20000, Western Blot 1/2500 - 1/20000
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Packaging:
Storage:Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:Constituents: 75mM PBS, 75mM Sodium chloride, 1mM EDTA. pH 7.2,
Preservative:0.02% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Background:

N epsilon carboxymethyl lysine (CML) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.

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Jump to: Primary Antibodies, Secondary Antibodies

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