CETP Antibody (NB300-558)
CETP Antibody (ATM192)
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Distributor Data...
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anti-Cholesteryl ester transfer antibody, anti-Lipid transfer protein I antibody, anti-Cholesteryl ester transfer protein precursor antibody, anti-Cholesteryl ester transfer protein plasma antibody, anti-Cholesteryl ester transfer protein antibody, |
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CETP Antibody (ATM192) Summary: | | Gene: | CETP |
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| Purity: | Protein A purified |
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| Host: | Mouse |
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| | Specificity: | Detects cholesteryl ester transfer protein (CETP) from human and rabbit tissues. |
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| Publications: | Antibody has at least 3 Background References. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CETP Products CETP Antibody (ATM192) Details: | Clone: | ATM192 |
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| Isotype: | IgG1 |
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| Immunogen: | Synthetic peptide: (131)CDSGRVRTDAPD(142)Immunizi ng peptide corresponds to the C-terminal amino acid residues 131-142 of the human CETP protein. |
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| Localization: | Secreted |
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Cross-reacts with Human and Rabbit.Not yet tested in other species. |
| Uses: | Western Blot, Immunoprecipitation, and ELISA This antibody detects a doublet at ~70 kDa from human serum representing CETP. This antibody can also be used to immunoprecipitate CETP activity from serum samples using protein G |
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| Dilutions: | ELISA Assay dependent,
immunoprecipitation Assay dependent,
Western Blot 1:400 |
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| Unit Size: | 0.1 ml |
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| Concentration: | 2.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS |
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| Preservative: | 0.05% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
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Images (1) Reviews (0) Related Products (10) Working with CETP
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Jump to: Publications, Images, Ask a Question
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Working with CETP
CETP Antibody (ATM192) Images (1) Western Blot: CETP Antibody (ATM192) [NB300-558] - Figure 1 shows a Western blot of CETP on human liver extract using NB300-558. |
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Publications (3)
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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