CDC42 Antibody (NB120-14241)
CDC42 Antibody
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Distributor Data...
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anti-CDC 42 antibody, anti-Small GTP binding protein CDC42 antibody, anti-GTP binding protein 25kD antibody, anti-Growth regulating protein antibody, anti-G25K GTP binding protein antibody, anti-G25K antibody, anti-dJ224A6.1.2 antibody, anti-dJ224A6.1.1 antibody, anti-Cell division cycle 42 isoform 2 antibody, anti-Cell division cycle 42 isoform 1 antibody, anti-Cell division cycle 42 antibody, anti-Cell division control protein 42 homolog antibody, anti-CDC42Hs antibody |
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CDC42 Antibody Summary: | | Gene: | CDC42 |
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| Purity: | Immunogen affinity purified |
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| Host: | Chicken |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CDC42 Products CDC42 Antibody Details: | Isotype: | IgY |
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| Immunogen: | Synthetic peptide, corresponding to amino acids 1-191 of CDC42. |
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| Localization: | Plasma membrane |
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Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Uses: | WB: Use at a dilution of 1/2000. Predicted molecular weight: 24 kDa. Tissue or cell immunostaining: Use at a starting dilution of 1/200.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
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| Dilutions: | Western Blot |
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| Unit Size: | 0.05 mg |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott Aldrich syndrome protein (NWASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.
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Images (1) Reviews (0) Related Products (18) Exploring CDC42 Working with CDC42
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Jump to: Publications, Images, Ask a Question
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Working with CDC42
CDC42 Antibody Images (1) E coli-derived fusion protein as test antigen. Affi-anti-CDC42 IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-BB1 ) |
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Publications (1)
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (3)Peptides and ProteinsPrimary Antibodies (5)RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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