CDC42 Antibody (H00000998-D01P)

CDC42 Antibody

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CDC42 Antibody Summary:
Species:Hu
Applications:ELISA, WB
Clonality:Polyclonal
Gene:CDC42
Purity:Protein A purified
Host:Rabbit
Specificity:Reacts with cell division cycle 42 (GTP binding protein, 25kDa).
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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CDC42 Antibody Details:
Immunogen:CDC42 (NP_001782.1, 1 a.a. ~ 191 a.a) full-length human protein.
Epitope:MQTIKCVVVGDGAVGKTCLLISYTTNKFPS EYVPTVFDNYAVTVMIGGEPYTLGLFDTAG QEDYDRLRPLSYPQTDVFLVCFSVVSPSSF ENVKEKWVPEITHHCPKTPFLLVGTQIDLR DDPSTIEKLAKNKQKPITPETAEKLARDLK AVKYVECSALTQKGLKNVFDEAILAALEPP EPKKSRRCVLL
Species Reactivity:

Human

Applications:
Uses:This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.
Dilutions:ELISA, Western Blot
Unit Size:0.1 mg
Concentration:Please see the vial label for concentration.
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:1x PBS, pH 7.2
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: CDC42
Entrez998 (Human)
Swiss ProtNP_001782.1 (Human)
 
Background:

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]

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Working with CDC42

CDC42 Antibody Images (1)
Western Blot analysis of CDC42 expression in transfected 293T cell line by CDC42 MaxPab rabbit polyclonal antibody.

Lane 1: CDC42 transfected lysate(21.30 KDa).
Lane 2: Non-transfected lysate.
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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CDC42 in Context


Novus Explorer for CDC42 gene

Try our bioinformatic tool that shows the relationships between CDC42 and other genes, diseases, pathways and post-translational modifications.