CDC42 Antibody (NBP1-44435)
CDC42 [p Ser71] Antibody (EP221Y)
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anti-CDC42Hs antibody, anti-CDC 42 antibody, anti-Small GTP binding protein CDC42 antibody, anti-GTP binding protein 25kD antibody, anti-Growth regulating protein antibody, anti-G25K GTP binding protein antibody, anti-G25K antibody, anti-dJ224A6.1.2 antibody, anti-dJ224A6.1.1 antibody, anti-Cell division cycle 42 isoform 2 antibody, anti-Cell division cycle 42 isoform 1 antibody, anti-Cell division cycle 42 antibody, anti-Cell division control protein 42 homolog antibody, anti-CDC42Hs antibody |
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CDC42 [p Ser71] Antibody (EP221Y) Summary: | | Gene: | CDC42 |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | Specificity: | The antibody only detects Rac1/Cdc42 phosphorylated on Serine 71. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CDC42 Products CDC42 [p Ser71] Antibody (EP221Y) Details: | Clone: | EP221Y |
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| Isotype: | IgG |
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| Immunogen: | A phospho-specific peptide corresponding to residues surrounding Serine 71 of human Rac1/Cdc42 was used as an immunogen. |
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| Modification: | p Ser71 |
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| Uses: | This product is useful for: Western Blot, Immunocytochemistry. In Western blot this antibody detects a band at approximately 23kDa. |
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| Dilutions: | Western Blot 1:1000-10000, Immunocytochemistry 1:100-250 |
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| TMW: | 23 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 50mM Tris-Glycine [pH 7.4] with 0.15M NaCl, 40% Glycerol and 0.05% BSA |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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