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CD44 Antibody (NB100-2710)

CD44 Antibody (P2A1)

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CD44 Antibody (P2A1) Summary:
Species:Hu
Applications:FACS, IHC-P, IP
Clonality:Monoclonal
Gene:CD44
Purity:IgG purified
Host:Mouse
Specificity:CD44 (P2A1)
Publications:Antibody has at least 1 Background Reference.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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CD44 Antibody (P2A1) Details:
Clone:P2A1
Isotype:IgG2a
Immunogen:Ocular melanoma cell line (V+B2).
Localization:Type I membrane protein
Marker:Cell membrane Marker
Species Reactivity:

Cross-reacts with Human.

Applications:
Uses:Flow Cytometry, Immunohistochemistry-Paraffin, Immunoprecipitation
Dilutions:Flow Cytometry assay dependent , immunoprecipitation assay dependent, Immunohistochemistry-Paraffin assay dependent
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Packaging:
Storage:Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:PBS
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: CD44
Entrez960 (Human)
 
Background:

CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.
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1 Background References
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Working with CD44

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Publications (1)

CD44 Antibody (P2A1) Background References:

  1. Nath D et al. Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin. Immunology 98:213-9 (1999).
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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CD44 in Context

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CD44 in the News (1):
Novus Explorer for CD44 gene
Try our bioinformatic tool that shows the relationships between CD44 and other genes, diseases, pathways and post-translational modifications.