CD44 Antibody (F10-44-2) [R-Phycoerythrin] (NB100-63806)

CD44 Antibody (F10-44-2) [R-Phycoerythrin] (NB100-63806) ( 100 Tests)

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	Catalog Number	NB100-63806
	Size(s)	100 Tests	Price:
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anti-Phagocytic glycoprotein I antibody, anti-Hermes antigen antibody, anti-PGP-I antibody, anti-GP90 lymphocyte homing/adhesion receptor antibody, anti-PGP-1 antibody, anti-CD44 antigen antibody, anti-Epican antibody, anti-LHR antibody, anti-CDw44 antibody, anti-HUTCH-I antibody, anti-homing function and Indian blood group system antibody, anti-ECMR-III antibody, anti-hematopoietic cell E- and L-selectin ligand antibody, anti-Phagocytic glycoprotein 1 antibody, anti-epican antibody, anti-Hyaluronate receptor antibody, anti-chondroitin sulfate proteoglycan 8 antibody, anti-Heparan sulfate proteoglycan antibody, anti-cell surface glycoprotein CD44 antibody, anti-Extracellular matrix receptor III antibody, anti-Pgp1 antibody, anti-MC56 antibody, anti-IN antibody, anti-HCELL antibody, anti-CSPG8 antibody, anti-MIC4MGC10468 antibody, anti-MDU3CDW44 antibody, anti-MDU2CD44 antigen (homing function and Indian blood group system) antibody, anti-CD44R antibody, anti-CD44 molecule (Indian blood group) antibody

CD44 Antibody (F10-44-2) [R-Phycoerythrin] Summary:

Species:	Hu	Gene:	CD44
Applications:	FACS	Purity:	Protein G purified
Clonality:	Monoclonal	Host:	Mouse
Specificity:	NB100-63806 recognizes the human CD44 cell surface antigen, a 100kD glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and of the breast. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.
Publications:	NB100-63806 has at least 5 Background References

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CD44 Antibody (F10-44-2) [R-Phycoerythrin] Details:

Conjugate:	R-Phycoerythrin
Clone:	F10-44-2
Isotype:	IgG2a
Immunogen:	Human T lymphocytes
Marker:	Cell membrane Marker

Species Reactivity:

Cross reacts with Human.

Applications:

Uses:	Flow Cytometry
Dilutions:	Flow Cytometry
Unit Size:	100 Tests
Concentration:	Lyoph
Conjugated Antibodies:	4 Conjugated Antibodies

Packaging:

Storage:	Store at 4°C. Do not freeze.
Buffer:	Phosphate buffered saline pH7.2 lyophilized
Preservative:	0.09% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: CD44

Entrez:	960 (Human)
Uniprot:	P16070 (Human)

Related Genes:

Background:

CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.

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CD44 Antibody (F10-44-2) [R-Phycoerythrin] Images (1)

	Flow Cytometry: CD44 Antibody (F10-44-2) [NB100-63806] - Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD44:RPE

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Publications (5)

CD44 Antibody (F10-44-2) [R-Phycoerythrin] Background References:

Roscic - Mrkic, B. et al. (2003) RANTES (CCL5) uses the proteoglycan CD44 as an auxiliary receptor to mediate cellular activation signals HIV - 1 enhancement. Blood. 102: 1169
Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49 (2): 97-110.

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Cattoretti, G. et al. (1993) Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections J. Pathol. 171:83-98.
Daar, A.S. Fabre, J.W. (1981) Demonstration with monoclonal antibodies of an unusual mononuclear cell infiltrate loss of normal epithelial membrane antigens in human breast carcinomas Lancet. 2: 434-438.
Dalchau, R. et al. (1980) Monoclonal antibody to a human brain granulocyte T lymphocyte antigen probably homologous to the W3/13 antigen of the rat. Eur. J. Immunol. 10: 745-750.