CD30 Antibody (NB100-77396)
CD30 Antibody (mCD30.1)
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anti-CD 30 antibody, anti-Tumor necrosis factor receptor superfamily member 8 antibody, anti-TNFRSF8 antibody, anti-Lymphocyte activation antigen CD30 antibody, anti-Ki1 antibody, anti-KI 1 antigen antibody, anti-Ki 1 antibody, anti-D1S166E antibody, anti-Cytokine receptor CD30 antibody, anti-CD30L receptor antibody, anti-CD30 antigen antibody, anti-CD153 antibody, |
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CD30 Antibody (mCD30.1) Summary: | | Gene: | TNFRSF8 |
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| Purity: | Immunogen affinity purified |
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| Host: | Armenian Hamster |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD30 Products CD30 Antibody (mCD30.1) Details: | Clone: | mCD30.1 |
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| Isotype: | IgG |
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| Immunogen: | Mouse CD30-mouse IgG1 fusion protein |
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| Uses: | Fflow cytometry / FACS analysis For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one million cells in 100 microliter volume. |
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| Dilutions: | Flow Cytometry |
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| Unit Size: | 0.5 mg |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Phosphate-buffered solution, pH 7.2 |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkin's and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
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Images (1) Reviews (0) Related Products (45) Exploring CD30 Working with CD30
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Jump to: Publications, Images, Ask a Question
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Working with CD30
CD30 Antibody (mCD30.1) Images (1) Con A-stimulated (3 days)splenocytes stained with purified mCD30.1, then detected with biotinylated anti-Armenian hamster IgG followed by Sav-PE |
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Publications (3)CD30 Antibody (mCD30.1) Background References:- Gedrich, R.W., et al., 1996. J. Biol. Chem. 271:12852.
- Falini, B., et al., 1995. Blood 85:1.
more... - Barclay, A., et al., 1997. The Leukocyte Antigen FactsBook, Academic Press.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Activated T, B and NK cells, monocytes
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Lysates (1)Peptides and ProteinsPrimary Antibodies (40)RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Armenian Hamster IgG Antibody (HTK888) | NB120-18474 | ArHa | FACS, ICC, IF, IHC-P, IP, WB | | | | | | Golden Syrian/Armenian Hamster IgG, H/L Chains Antibody [DyLight 488] | NBP1-73008 | ArHa, SyHa | FLISA, IF, WB | (1) | | | | | Golden Syrian/Armenian Hamster IgG, H/L Chains Antibody [DyLight 549] | NBP1-73009 | ArHa, SyHa | FLISA, IF, WB | (1) | | | | | Golden Syrian/Armenian Hamster IgG, H/L Chains Antibody [DyLight 649] | NBP1-73010 | ArHa, SyHa | FLISA, IF, WB | (1) | | | | | Golden Syrian/Armenian Hamster IgG, H/L Chains Antibody [DyLight 680] | NBP1-73011 | ArHa, SyHa | FLISA, IF, WB | (1) | | | | | See All » |
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