CD30 Antibody (NB500-562)
CD30 Antibody (MEM-268)
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anti-CD 30 antibody, anti-Tumor necrosis factor receptor superfamily member 8 antibody, anti-TNFRSF8 antibody, anti-TNFRSF 8 antibody, anti-Lymphocyte activation antigen CD30 antibody, anti-Ki1 antibody, anti-KI 1 antigen antibody, anti-Ki 1 antibody, anti-D1S166E antibody, anti-Cytokine receptor CD30 antibody, anti-CD30L receptor antibody, anti-CD30 antigen antibody, |
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CD30 Antibody (MEM-268) Summary: | | Gene: | TNFRSF8 |
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| Purity: | Protein A purified |
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| Host: | Mouse |
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| | Specificity: | CD30 (MEM-268) |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD30 Products CD30 Antibody (MEM-268) Details: | Clone: | MEM-268 |
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| Isotype: | IgG |
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| Immunogen: | Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line) |
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| Localization: | Type I membrane protein (long isoform); cytoplasmic (short isoform). |
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| Epitope: | The antibody recognizes the extracellular part of CD30 antigen. |
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| Uses: | Flow Cytometry |
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| Dilutions: | Flow Cytometry,
Immunohistochemistry-Paraffin 1:200 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS. pH 7.4 |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkin's and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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