CD30 Antibody (NB120-871)
CD30 Antibody (Ber-H2)
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anti-CD 30 antibody, anti-Tumor necrosis factor receptor superfamily member 8 antibody, anti-TNFRSF8 antibody, anti-Lymphocyte activation antigen CD30 antibody, anti-Ki1 antibody, anti-KI 1 antigen antibody, anti-Ki 1 antibody, anti-D1S166E antibody, anti-Cytokine receptor CD30 antibody, anti-CD30L receptor antibody, anti-CD30 antigen antibody, anti-CD153 antibody, |
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CD30 Antibody (Ber-H2) Summary: | | Gene: | TNFRSF8 |
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| Purity: | IgG purified |
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| Host: | Mouse |
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| | Specificity: | This reacts with mononuclear cells in Hodgkin lymphoma, Reed-Sternberg cells and most anaplastic large cell lymphomas. It stains large cells localized around the B cell in the lymphoid tissues. This stains the cell surface and the golgi |
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| Publications: | Antibody has at least 1 Background Reference. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD30 Products CD30 Antibody (Ber-H2) Details: | Clone: | Ber-H2 |
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| Isotype: | IgG1 Kappa |
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| Immunogen: | BALB/C mice were injected with L428 cell line cells. |
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| Localization: | Type I membrane protein (long isoform); cytoplasmic (short isoform). |
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Cross-reacts with Human.Not yet tested in other species. |
| Uses: | This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. |
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| Dilutions: | Immunohistochemistry-Frozen Neat, Immunohistochemistry-Paraffin Neat |
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| Unit Size: | 6.0 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 1 Positive Controls |
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Notes: This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only. Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS |
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| Preservative: | Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkin's and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
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Reviews (0) Related Products (45) Exploring CD30 Working with CD30
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CD30 Antibody (Ber-H2) Images (0)
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Publications (1)CD30 Antibody (Ber-H2) Background References:- Pallesen G The diagnostic significance of the CD30 (Ki-1) antigen. Histopathology 16:409-13 (1990). PUBMED:2163354Schwarting R et al. BER-H2: a new anti-Ki-1 (CD30) monoclonal antibody directed
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsLysates (1)Peptides and ProteinsPrimary Antibodies (26)RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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