CD3 Antibody (NBP1-30427)
CD3 Antibody (APA1/1) [PE]
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anti-CD 3E antibody, anti-TCRE antibody, anti-T3E antibody, anti-CD3e molecule epsilon CD3 TCR complex antibody, anti-CD3e molecule epsilon antibody, anti-CD3E antibody, anti-CD3 TCR complex antibody, anti-CD3 epsilon antibody |
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CD3 Antibody (APA1/1) [PE] Summary: | | Gene: | CD3E |
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| Purity: | IgG purified |
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| Host: | Mouse |
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| | Specificity: | The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation. |
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| Publications: | Antibody has been mentioned in at least 8 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD3 Products CD3 Antibody (APA1/1) [PE] Details: | Conjugate: | PE |
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| Clone: | APA1/1 |
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| Isotype: | IgG1 |
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| Immunogen: | Purified human CD3 proteins isolated from thymus |
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| Uses: | The reagent is designed for Flow Cytometry analysis. |
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| Dilutions: | Flow Cytometry,
ImmunoPrecipitation 1:50,
Western Blot 1:1000,
Immunohistochemistry-Frozen 1:200,
Immunocytochemistry |
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| Unit Size: | 0.1 mg |
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| Concentration: | 0.1 mg/ml |
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Notes: Store in the dark, avoid prolonged exposure to light. Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS containing 0.2% (w/v) high-grade protease free BSA as a stabilizing agent. |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD3 epsilon is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3 epsilon, one CD3 gamma, one CD3 delta, one CD3 zeta (CD247), and a T-cell receptor ( alpha/ beta or gamma/ delta) heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. The UCHT1 antibody is able to induce T cell activation.
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CD3 Antibody (APA1/1) [PE] Images (0)
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Publications (8)
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Jump to: Primary Antibodies, Secondary Antibodies
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Related ProductsPrimary Antibodies (64)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| CD3 Antibody (N26-R) | NBP1-79054 | Hu | IHC-Fr, IHC-P | (1) | | | | | CD3 Antibody (APA1/1) | NBP1-30426 | Hu, Mu | FACS, ICC, IHC-Fr, IP, WB | | (1) | | | | CD3 Antibody (SP7) | NBP1-49794 | Bb, Ca, Fe, Hu, Mk | IHC-P, WB | (2) | | | | | CD3 Antibody (UCH-T1) | NB100-2726 | Hu | FACS, IF, IHC-Fr, IP, RI | | (7) | | | | CD3 Antibody | NBP1-72167 | Hu, Mu, Rt | ELISA, FACS, IHC, IP, WB | (1) | | | | | ... and 59 more. See All » |
Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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