CD14 Protein

Protein Type: Biologically Active Species: Hu Applications: WB, Func, B/N	Gene: CD14 Purity: Protein
Specificity: This product has a purity greater than 98% by SDS-PAGE gel and HPLC analyses. The endotoxin level is less than 0.1 ng per ug (1EU/ug).
See All CD14 Products See All CD14 Related Products: Antibody Pairs Lysates Peptides and Proteins Primary Antibodies RNAi

Immunogen:	TTPEPCELDD EDFRCVCNFS EPQPDWSEAF QCVSAVEVEI HAGGLNLEPF LKRVDADADP RQYADTVKAL RVRRLTVGAA QVPAQLLVGA LRVLAYSRLK ELTLEDLKIT GTMPPLPLEA TGLALSSLRL RNVSWATGRS WLAELQQWLK PGLKVLSIAQ AHSPAFSCEQ VRAFPALTSL DLSDNPGLGE RGLMAALCPH KFPAIQNLAL RNTGMETPTG VCAALAAAGV QPHSLDLSHN SLRATVNPSA PRCMWSSALN SLNLSFAGLE QVPKGLPAKL RVLDLSCNRL NRAPQPDELP EVDNLTLDGN PFLVPGTALP HEGSMNSGVV P

Entrez:	929 (Human)
Related Genes:	TNF, TLR4, NOD2, CTLA4, HLA-DQA1, IL6, ITGAM, TLR2, LBP, IL10, IL4, CD4, CD34, CD3E, FCGR3B, FCGR3, CSF2, FCGR3A, LY96, PTPRC, DCX, TBX10, CD8A, CD86, CD19, IFNG, ICAM1, ANPEP, EHHADH, CD33, CD80, ITGAX, ITGB2, LTBR, NFKB1, IL1B, IL2, CD83, IL8, FUT4

CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.

Reactivity:	Human.

Uses:	This product is useful for Western Blot, Functional Assays, and Blocking/Neutralizing.
Dilutions:	Blocking/Neutralizing, Functional, Western Blot

This fully active recombinant protein is expressed in E. coli and is fully functional. Reconstitue with sterile water.

Buffer:	lyophilized protein
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.