CD11b Antibody (NB600-1327)
CD11b Antibody (M1/70.15)
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anti-Cell Surface Glycoprotein MAC1 Alpha Subunit antibody, anti-Neutrophil Adherence Receptor antibody, anti-MO1A antibody, anti-MAC1A antibody, anti-ITGAM antibody, anti-CR3A antibody, anti-Complement Component Receptor 3 Alpha antibody, |
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CD11b Antibody (M1/70.15) Summary: | | Gene: | ITGAM |
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| Purity: | IgG purified |
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| Host: | Rat |
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| | Specificity: | Detects the CD11b antigen (mW170 and 95kD) also known as Mac-1 antigen, found on mouse macrophages, their precursors and granulocytes. |
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| Publications: | Antibody has been mentioned in at least 5 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD11b Products CD11b Antibody (M1/70.15) Details: | Clone: | M1/70.15 |
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| Isotype: | IgG2b |
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| Immunogen: | T cell enriched splenocytes from B10 mice |
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| Marker: | Microglia Marker |
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Cross-reacts with Human, Mouse and Rabbit. Not yet tested in other species. |
| Uses: | Flow Cytometry Use at a dilution of 1/200 (10ul per million cells). IHC-P: Perform enzymatic antigen retrieval before commencing with IHC staining protocol. NB600-1327 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. May also be used on frozen sections. |
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| Dilutions: | Flow Cytometry 1:50-1:200, Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | 50% Glycerol, PBS |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes and is commonly used as a microglial marker in nervous tissue.
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Images (2) Reviews (0) Related Products (55) Exploring CD11b Working with CD11b
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Jump to: Publications, Images, Ask a Question
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Working with CD11b
CD11b Antibody (M1/70.15) Images (2)-Flow-Cytometry-NB600-1327-img0002.jpg "Flow Cytometry: CD11b Antibody (M1/70.15) [NB600-1327] - Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b (NB600-1327).") Flow Cytometry: CD11b Antibody (M1/70.15) [NB600-1327] - Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b (NB600-1327). | -Flow-Cytometry-NB600-1327-img0001.jpg "Flow Cytometry: CD11b Antibody (M1/70.15) [NB600-1327] - Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b") Flow Cytometry: CD11b Antibody (M1/70.15) [NB600-1327] - Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b |
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Publications (5)
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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPeptides and ProteinsPrimary Antibodies (53)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| CD11b Antibody | NB110-89474 | Bv, Hu, Mu, Rt | ICC, IF, IHC-P, WB | (3) | (3) | | | | CD11b Antibody (M1/70) | NBP1-45013 | Hu, Mk, Mu, Rb | FACS, Func, IHC-Fr, IP | | (4) | | | | CD11b Antibody (EP1345Y) | NB110-55684 | Hu, Mu(-), Rt(-) | FACS, ICC, IHC-P, IP, WB | (2) | (2) | | | | CD11b Antibody | NBP1-50231 | Hu, Rt | FACS, IHC-Fr, IHC-P, IP | (1) | | | | | CD11b Antibody (Bear-1) | NBP1-42113 | Hu | IF, IHC-Fr, IP | | | | | | ... and 48 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rat IgG, H/L Chains Antibody [DyLight 800] | NBP1-72993 | Rt | DB, FLISA, IF, WB | (2) | | | | | Rat IgG Antibody | NB120-7092 | Rt | ELISA, FLISA, IHC-P, IP, WB | (2) | | | | | Rat IgG Antibody [Cy3.5] | NB120-6954 | Rt | FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | Rat IgG Antibody [Cy2] | NB120-6952 | Rt | FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | Rat IgG, H/L Chains Antibody [DyLight 549] | NBP1-72812 | Rt | FLISA, IF, WB | (2) | | | | | See All » |
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