Jump to Information on CD11b Antibody (NBP1-42075)
CD11b Antibody (EPR1344) Summary
||Human, Mouse, Rat (Negative)
||WB, FLOW, ICC/IF, IHC, IHC-P
||All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
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CD11b Antibody (EPR1344) Details
||A synthetic peptide corresponding to residues in human CD11b was used as an immunogen.
Human. For Mouse this antibody is recommended for Western Blot only.
||Read 1 rated 4 using NBP1-42075 in the following species:
- Western Blot 1:1000-5000
- Flow Cytometry 1:100
- Immunocytochemistry/Immunofluorescence 1:100-250
- Immunohistochemistry 1:10-1:2000
- Immunohistochemistry-Paraffin 1:100-250
In Western blot this antibody detects a band at approximately 170 kDa.
Average Rating: 4
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Protocols and FAQs
Controls & Support Products
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5675,063 and 7,429,487, owned by Abcam.
Packaging, Storage & Formulations
||Store at -20C. Avoid freeze-thaw cycles.
||PBS 49%, Glycerol 50%, BSA 0.05%
||Please see the vial label for concentration.
||0.01% Sodium Azide
||This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Alternate Names for CD11b
- Neutrophil adherence receptor
- CD11b antigen
- neutrophil adherence receptor alpha-M subunit
- CR-3 alpha chain
- macrophage antigen alpha polypeptide
- CD11 antigen-like family member B
- integrin alpha-M
- Leukocyte adhesion receptor MO1
- antigen CD11b (p170)
- Cell surface glycoprotein MAC-1 subunit alpha
- CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide)
- integrin, alpha M (complement component 3 receptor 3 subunit)
Related Products by Gene
CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it
mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.