CD11b Antibody (EPR1344) 0.1 ml Microglia Marker, Myeloid Marker

CD11b NBP1-42075

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  • All CD11b Products
  • 3 reviews  
  • Alternate Names
     

Ordering Information: NBP1-42075

Catalog NumberNBP1-42075
  • FormUnconjugated
  • Size(s)0.1 ml
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CD11b Antibody (EPR1344) Summary

 
Species Human, Mouse, Rat (Negative)
Tested Applications WB, FLOW, ICC/IF, IHC, IHC-P
Clonality Monoclonal
Host Rabbit
Gene ITGAM
Purity IgG purified
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CD11b Antibody (EPR1344) Details

 
Clone EPR1344
Isotype IgG
Marker Microglia Marker, Myeloid Marker
Immunogen A synthetic peptide corresponding to residues in human CD11b was used as an immunogen.

Species Reactivity

 
Human. For Mouse this antibody is recommended for Western Blot only.
Reviewed Species Read 3 rated 4  using NBP1-42075 in the following species:
 

Applications/Dilutions

 
Dilutions
  • Western Blot 1:1000-5000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100-250
  • Immunohistochemistry 1:10-1:2000
  • Immunohistochemistry-Paraffin 1:100-250
Application Notes

In Western blot this antibody detects a band at approximately 170 kDa.

Reviewed Applications
Read 2 reviews rated 4  using
NBP1-42075 in the following applications:

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Reviews

Average Rating: 4 
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Controls & Support Products

Research Tools

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Notes

 
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5675,063 and 7,429,487, owned by Abcam.

Packaging, Storage & Formulations

 
Storage Store at -20C. Avoid freeze-thaw cycles.
Buffer Glycerol 50%, BSA 0.05%, pH: 7.40
Unit Size 0.1 ml
Concentration Please see the vial label for concentration.
Preservative 0.01% Sodium Azide
Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

 
Gene Symbol ITGAM
Entrez
Uniprot

Alternate Names for CD11b

 
  • Neutrophil adherence receptor
  • SLEB6
  • CD11b antigen
  • MAC1A
  • neutrophil adherence receptor alpha-M subunit
  • CR-3 alpha chain
  • macrophage antigen alpha polypeptide
  • CD11 antigen-like family member B
  • integrin alpha-M
  • Leukocyte adhesion receptor MO1
  • antigen CD11b (p170)
  • Cell surface glycoprotein MAC-1 subunit alpha
  • MO1A
  • MAC-1
  • CR3AMGC117044
  • CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide)
  • CD11b
  • integrin, alpha M (complement component 3 receptor 3 subunit)

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Background

 
CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.