CD11b Antibody (NB110-57102)
CD11b Antibody (EP1345Y)
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anti-CD11b antigen antibody, anti-Neutrophil Adherence Receptor antibody, anti-MO1A antibody, anti-MGC117044 antibody, anti-MAC1A antibody, anti-MAC1 antibody, anti-MAC 1 antibody, anti-Leukocyte Adhesion Receptor MO1 antibody, anti-ITGAM antibody, anti-integrin alpha M complement component 3 receptor 3 subunit antibody, anti-Integrin Alpha M antibody, anti-CR3A antibody, anti-CR3 Alpha Chain antibody, anti-CR 3 alpha chain antibody, anti-Complement Component Receptor 3 Alpha antibody, anti-Cell Surface Glycoprotein MAC1 Alpha Subunit antibody, anti-Cell surface glycoprotein MAC 1 alpha subunit antibody, |
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CD11b Antibody (EP1345Y) Summary: | | Gene: | ITGAM |
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| Purity: | Tissue culture supernatant |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD11b Products CD11b Antibody (EP1345Y) Details: | Clone: | EP1345Y |
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| Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to C-terminus of human CD11b/ITAM protein was used as immunogen |
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| Marker: | Microglia Marker |
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Reacts in Human. Does not react to Mouse or Rat. |
| Uses: | This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 170kDa. |
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| Dilutions: | Western Blot 1:1000-10000, Immunohistochemistry-Paraffin 1:100-1:250, Immunocytochemistry 1:100-1:250, Immunoprecipitation 1:80, Flow Cytometry 1:20 |
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| TMW: | 170 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | This product is unpurified. Concentration is not relevant. |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 0 |
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| Preservative: | 0.25% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Integrin alpha-M (ITAM, ITGAM, CD11b, MAC-1 alpha subunit, CR3 alpha chain) is the alpha subunit of ITAM/beta-2 complex (CD11b/CD18, Mac-1), a leukocyte adhesion heterodimeric glycoprotein (1). ITAM belongs to integrin alpha chain family and it is predominately presented in human myeloid cells, NK1 cells, monocytes, and granulocytes. ITAM/beta-2 complex is a receptor for fibrinogen (binding to P1 and P1 peptides of gamma chain), factor X, and ICAM1. ITAM/beta-2 is implicated in adhesive interactions of monocytes, macrophages, and granulocytes. It is also linked to mediation of complement-coated particle uptake (2).
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Images (2) Reviews (0) Related Products (55) Working with CD11b
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Jump to: Publications, Images, Protocols/Procedures, Ask a Question
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Working with CD11b
CD11b Antibody (EP1345Y) Images (2) Immunohistochemistry: CD11b/ITAM (C-term) Antibody (EP1345Y) [NB110-57102] - Immunohistochemical analysis of paraffin-embedded human spleen using anti-ITAM (cat. # 110-57102). |  Western Blot: CD11b/ITAM (C-term) Antibody (EP1345Y) [NB110-57102] - Western blot analysis on TF-1 lysate using anti-ITAM (cat. #110-57102), dilution 1:20,000 |
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Publications (2)CD11b Antibody (EP1345Y) Background References:- Barden A et al. Clin Sci (Lond). 92(1):37-44m 1997.
- Corbi AL et al. J. Biol. Chem. 263(25):12403-12411, 1998.
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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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