CD105 Antibody (NB100-77666)
CD105 Antibody (MJ7/18)
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Distributor Data...
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anti-Enoglin antibody, |
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CD105 Antibody (MJ7/18) Summary: | | Gene: | ENG |
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| Purity: | Immunogen affinity purified |
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| Host: | Rat |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional CD105 Products CD105 Antibody (MJ7/18) Details: | Clone: | MJ7/18 |
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| Isotype: | IgG2a Kappa |
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| Immunogen: | inflamed mouse skin |
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| Marker: | Hematopoietic Stem Cell Marker |
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| Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry-frozen section. It is recommended that the reagent be titrated for optimal performance for each application. |
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| Dilutions: | Flow Cytometry ,
immunoprecipitation ,
Western Blot ,
Immunohistochemistry-Frozen |
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| Unit Size: | 0.5 mg |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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| Conjugated Antibodies: | 3 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS [pH 7.2] |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.
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Reviews (0) Related Products (52) Exploring CD105 Working with CD105
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Jump to: Publications, Ask a Question
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Working with CD105
CD105 Antibody (MJ7/18) Images (0)
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Publications (3)CD105 Antibody (MJ7/18) Background References:- Barbara, N. P., et al., 1999. J. Bio. Chem. 274:584.
- Cheifetz, S., et al., 1992. J. Bio. Chem. 267:19027.
more... - Gougos, A., M. Letarte, 1988. J. Immunol. 141:1925.
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Jump to: Conjugated Antibodies, Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated AntibodiesPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotropholast
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Antibody Pairs (3)Lysates (2)Peptides and ProteinsPrimary Antibodies (36)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| CD105 Antibody | NBP1-91212 | Hu | IF, IHC-P, WB | (3) | | | | | CD105 Antibody (MJ7/18) | NB600-1011 | Mu | FACS, IHC-Fr, IP, WB | | (1) | | | | CD105 Antibody (MEM-229) | NB110-58718 | Hu, Po | FACS, ICC, IHC-Fr, WB | | | | | | CD105 Antibody (E9) | NBP1-42383 | Hu, Rt | ELISA, FACS, IHC-Fr, IP, WB | | | | | | CD105 Antibody (MEM-226) | NB500-452 | Hu | FACS, IP, WB | (1) | | | | | ... and 31 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rat IgG, H/L Chains Antibody [DyLight 800] | NBP1-72993 | Rt | DB, FLISA, IF, WB | (2) | | | | | Rat IgG Antibody | NB120-7092 | Rt | ELISA, FLISA, IHC-P, IP, WB | (2) | | | | | Rat IgG Antibody [Cy3.5] | NB120-6954 | Rt | FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | Rat IgG Antibody [Cy2] | NB120-6952 | Rt | FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | Rat IgG, H/L Chains Antibody [DyLight 549] | NBP1-72812 | Rt | FLISA, IF, WB | (2) | | | | | See All » |
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