CCR2 Antibody (E68) (NB110-55674)

CCR2 Antibody (E68) (NB110-55674) (0.1 ml)

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	Catalog Number	NB110-55674
	Size(s)	0.1 ml	Price:
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anti-CCR2B antibody, anti-CD192 antigen antibody, anti-CCR2A antibody, anti-monocyte chemotactic protein 1 receptor antibody, anti-C-C CKR-2 antibody, anti-MCP-1 receptor antibody, anti-CCR-2 antibody, anti-C-C chemokine receptor type 2 antibody, anti-Monocyte chemoattractant protein 1 receptor antibody, anti-FLJ78302 antibody, anti-CKR2 antibody, anti-MGC168006 antibody, anti-CD192 antibody, anti-CMKBR2MGC111760 antibody, anti-MCP-1-RMGC103828 antibody, anti-CC-CKR-2CKR2B antibody, anti-CKR2A antibody, anti-chemokine (C-C motif) receptor 2 antibody

CCR2 Antibody (E68) Summary:

Species:	Hu, Mu, Rt(-)	Gene:	CCR2
Applications:	FACS, IHC-P, IP	Purity:	IgG purified
Clonality:	Monoclonal	Host:	Rabbit
Specificity:	The antibody does not cross-react with other CKR family members.
Publications:	NB110-55674 has been mentioned in at least 18 Publications

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CCR2 Antibody (E68) Details:

Clone:	E68
Isotype:	IgG
Immunogen:	A synthetic peptide corresponding to the N-terminal residues of the human C-C chemokine receptor type 2 was used as immunogen.

Species Reactivity:

Reacts in Human and Mouse. Does not react in Rat.

Applications:

Uses:	This product is useful for: Immunohistochemistry-Paraffin, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 42-52kDa.
Dilutions:	Flow Cytometry 1:25, Immunohistochemistry-Paraffin 1:100, Immunoprecipitation 1:50
MW:	47 kDa
Unit Size:	0.1 ml
Concentration:	Please see the vial label for concentration.
Positive Controls:	1 Positive Controls

Packaging:

Storage:	Store at -20°C. Avoid freeze-thaw cycles.
Buffer:	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA.
Preservative:	0.01% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: CCR2

Entrez:	729230 (Human)
	12772 (Mouse)
	60463 (Rat)
Uniprot:	P41597 (Human)

Related Genes:

Background:

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.