Bad Antibody (NB200-615)
Bad Antibody (Y208)
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Distributor Data...
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anti-Bcl-2 binding component 6 antibody, anti-Proapoptotic BH3 Only Protein antibody, anti-BclXL antibody, anti-BCL2L8 antibody, anti-Bcl2 Like 8 Protein antibody, anti-Bcl2 Associated Death Promoter antibody, anti-Bcl XL/Bcl 2 Associated Death Promoter antibody, anti-BCL X Binding Protein antibody, anti-BCL X / BCL 2 Binding Protein antibody, anti-Bcl 2 Binding Component 6 antibody, anti-Bcl 2 Antagonist of Cell Death antibody, anti-BBC6 antibody, anti-BBC2 antibody, anti-BBC 2 antibody |
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Bad Antibody (Y208) Summary: | | Gene: | BAD |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | Specificity: | The antibody does not cross-react with other Bcl-2 members. |
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| Publications: | Antibody has been mentioned in at least 1 Publication. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Bad Products Bad Antibody (Y208) Details: | Clone: | Y208 |
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| Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to residues in the N-term of human Bad was used as immunogen. |
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Reacts in Human, Mouse, Rat. |
| Uses: | This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 23kDa. |
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| Dilutions: | Western Blot 1:1000-10000, Immunohistochemistry-Paraffin 1:100-250, Immunocytochemistry 1:250-500, Immunoprecipitation 1:100, Flow Cytometry 1:50 |
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| TMW: | 23 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 56 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Bad is a pro-apoptotic member of the Bcl-2 family. Bad will bind preferentially Bcl-xL over Bcl-2 through its partial (9-16 a.a) BH3 domain. Additionally, Bad can reverse the death repressor activity of Bcl-xL but not of Bcl-2. Upon dephosphorylation, activated Bad translocates to the mitochondria and displace Bcl-2 from tBid sequestration to initiate mitochondrial dysfunction. The switching on/off of its phosphorylation by growth/survival factors regulates Bad activity.
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Images (3) Reviews (0) Related Products (55) Working with Bad
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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsAntibody Pairs (5)Lysates (3)Peptides and ProteinsPrimary Antibodies (28)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Bad Antibody | NBP1-88698 | Hu | IF, IHC-P, WB | (3) | | | | | Bad Antibody | NBP1-19451 | Hu, Mu, Rt | IF, IHC-P, WB | (2) | | | | | Bad Antibody | NBP1-61543 | Hu, Mu, Rt | ELISA, IHC, WB | (2) | | | | | Bad Antibody | NBP1-61813 | Hu, Mu, Rt | ELISA, IHC, WB | (2) | | | | | Bad Antibody | NBP1-61814 | Hu, Mu, Rt | ELISA, IHC, WB | (2) | | | | | ... and 23 more. See All » |
RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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![Immunohistochemistry: Bad Antibody (Y208) [NB200-615] - Immunohistochemical staining of paraffin-embedded human lymphoma using a anti-Bad (N-term)](http://images.novusbio.com/images/p_44f6051b947e3.jpg "Immunohistochemistry: Bad Antibody (Y208) [NB200-615] - Immunohistochemical staining of paraffin-embedded human lymphoma using a anti-Bad (N-term)")
![Immunohistochemistry: Bad Antibody (Y208) [NB200-615] - Immunohistochemical staining of paraffin-embedded human lymphoma using anti-Bad (N-term)](http://images.novusbio.com/images/p_44f604a3c1ecb.jpg "Immunohistochemistry: Bad Antibody (Y208) [NB200-615] - Immunohistochemical staining of paraffin-embedded human lymphoma using anti-Bad (N-term)")
![Western Blot: Bad Antibody (Y208) [NB200-615] - Western blot analysis on Hela cell lysate using anti-Bad (N-term), dilution 1:5,000.](http://images.novusbio.com/images/p_44f70cf433acf.jpg "Western Blot: Bad Antibody (Y208) [NB200-615] - Western blot analysis on Hela cell lysate using anti-Bad (N-term), dilution 1:5,000.")
